hypotrichosis type 6

hypotrichosis type 6

An autosomal recessive condition (OMIM:607903) characterised by a relative paucity of hair, involving mainly the scalp, chest, arms and legs, with abnormal thin and atrophic hair follicles and hair shafts. 

Molecular pathology
Defects in DSG4, which encodes desmoglein 4, a component of intercellular desmosomes that mediate cell–cell adhesion, cause hypotrichosis type 6.
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