A subnormal thyroxine concentration in the blood.
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Downstream effects of maternal hypothyroxinemia in early pregnancy: Nonverbal IQ and brain morphology in school-age children.
As there is no benefit in treatment of isolated maternal hypothyroxinemia, universal FT4 screening during preconception is not recommended.
sup][21] Correct establishment of reference intervals will directly affect the accuracy of disease diagnosis, and the TSH upper limit and the FT4 lower limit play key roles in the diagnosis of clinical/subclinical hypothyroidism or hypothyroxinemia.
ATLANTA -- Prenatal treatment of maternal subclinical hypothyroidism or hypothyroxinemia conferred no cognitive, behavioral, or neurodevelopmental benefit to children up to age 5.
Early maternal hypothyroxinemia alters histogenesis and cerebral cortex cytoarchitecture of the progeny.
Even though there is a state of hypothyroxinemia in normal pregnancy, it is more pronounced in pre-eclampsia.
7 Some authors have reported a relationship between hypothyroxinemia and mortality in seriously ill patients with sepsis.
Transient hypothyroxinemia in neonates with birth asphyxia delivered by Emergency cesarean section.
Hypothyroxinemia and TPO-antibody positivity are risk factors for premature delivery: the generation R study.
However, the effects of mild-to-moderate iodine deficiency (MMID) during pregnancy are not fully understood; emerging evidence suggests that MMID can cause gestational hypothyroxinemia, which may also have significant consequences for the fetus, and is often undetected (Suarez Rodriguez, Azcona San Julian, & Alzina de Aguilar, 2013).
Perinatal significance of isolated maternal hypothyroxinemia identified in the first half of pregnancy.
Maternal hypothyroxinemia during early pregnancy and subsequent child development: a 3-year follow-up study.