Accumulating evidence demonstrates that the effects of leptin to regulate the onset of puberty are thought to be mediated mainly by its receptor LEPR action on hypothalamic
neurons (Bellefontaine et al.
So they observed what happened when they selectively disrupted the hypothalamic
stem cells in middle-aged mice.
Suprasellar germ cell tumors (most commonly germinomas) arise from the hypothalamic
region and grow along the pituitary stalk.
These results suggest that chronic ethanol affects GH secretion primarily at the hypothalamic
level where it induces impairments in GHRH gene expression.
Our data demonstrated that i) Peripheral insulin injection dose not significantly affect the feed intake of chicks; ii) Peripheral insulin treatment dose not significantly alter the hypothalamic
INSR and appetite-related genes expression of NPY, POMC, and CRH.
GLP1RA have been studied in both euglycaemic and diabetic patients with moderate to severe hypothalamic
6] We are reporting a case of hypothalamic
hamartoma, initially presenting with laughing seizures.
Some recent studies have shown the association of rodent models of obesity and type 2 diabetes (T2D) with hypothalamic
injury and gliosis, which we can say is a potential cause of BCGS dysfunction.
At this time, Jahi does not fulfill California's statutory definition of death, which requires the irreversible absence of all brain function, because she exhibits hypothalamic
function and intermittent responsiveness to verbal commands.
The medical profession is aware of the fact that natural cortisol, produced by the middle layer adrenal cortex, works with the hypothalamic
pituitary axis in a negative feedback mechanism.
MSG-injected animals were screened for effectiveness of treatment by macroscopic observation of degeneration of the optic nerves at the time of sacrifice and monitoring medial basal hypothalamic
(MBH) levels of NPY mRNA.
The results indicate that the inhibitory effect of long-term feed restriction on LH secretion in prepubertal ewes is possibly because of a decrease in hypothalamic
expression of KiSS-1.