However, in patients with a BMI of greater than 28 and probable OSA, no difference in the number of respiratory events (obstructive apnoeas, hypopnoeas
or central apnoeas) was found between those given IV-PCA morphine compared with those given an 'opioid-sparing' analgesic regimen (IV-PCA tramadol, parecoxib and 'rescue-only' morphine), but there was a correlation between more than 15 respiratory events/hour and central apnoeas with total morphine dose (67).
An abnormal breathing event during objectively measured sleep was defined according to the common clinical criteria of either a complete cessation of airflow lasting 10 sec (apnoea) or a discernible reduction in airflow accompanied by a decrease of 4 per cent in oxyhaemoglobin saturation (hypopnoea
).The average number of episodes of apnoea and hypopnoea
per hour of sleep, the apnoea hypopnoea
index (AHI) was calculated.
Sleep - 1: Obstructive sleep apnoea/ hypopnoea
syndrome: definitions, epidemiology, and natural history.
Thoracoabdominal plethysmograph oro-nasal temperature thermistor and nasal-cannula-pressure transducer system were used to identify apnoeas and hypopnoeas
. Transcutaneous finger pulse oximetre was used to measure oxygen saturation.
Time course of changes in driving simulator performance with and without treatment in patients with sleep apnoea hypopnoea
Douglas, "Partners of patients with sleep apnoea/ hypopnoea
syndrome: effect of CPAP treatment on sleep quality and quality of life," Thorax, vol.
was defined as a reduction in amplitude of the primary airflow trace of at least 50% of the preceding amplitude and accompanied in <30 s by oxygen desaturation of 4% (12).
In this issue Chou and colleagues (7) report on a Taiwanese referral-based study demonstrating that unlike the apnoea hypopnoea
index; the oxygen desaturation index defined as the frequency of 4 per cent oxygen desaturation episodes per hour of sleep was significantly associated with hypercholesterolaemia (>200 mg/dl) and hypertriglyceridaemia (>150 mg/dl) even after taking into account confounding factors such as obesity as defined by body mass index.
Management of obstructive sleep apnoea/ hypopnoea
syndrome in adults.
The definition of hypopnoea
was a 50 per cent or greater reduction in airflow for a minimum of 10 seconds, associated with an equal to or greater more than a 4 per cent drop in Sp[O.sub.2] or an EEG alpha wave arousal (15,16).
4) TAI (Total Arousal Index) with oxygen drop/AHI (Apnoea Hypopnoea
Index) and OA are high in Group 1 patients.
A few periods of apnoea or hypopnoea
may arise during REM sleep.Thus in the normal adult, there is an orderly progression from wakefulness to sleep onset to NREM and then to REM sleep.