Nicola, 37, suffers from
hypophosphataemia, a rare genetic disorder that requires a modified vehicle to get around.
Hypophosphataemia in old patients is associated with the refeeding syndrome and reduced survival.
Blood tests revealed hypokalaemia (K+ = 2.2 mmol/L) and
hypophosphataemia (PO4 = 0.35mmol/L).
In general, Mg deficiency has been associated with a number of clinical manifestations such as neuromuscular abnormalities, tetany, seizures, cardiac problems like atrial and ventricular arrhythmias, cardiac insufficiency, coronary spasm, torsades de pointes, sudden death, respiratory problems like respiratory muscle weakness and bronchospasm associated with electrolyte abnormalities including hypokalaemia, hypocalcaemia, hyponatraemia and
hypophosphataemia. [3,4,5]
General G1 G2 p (n = 531) (n = 276) (n = 255) value Hypotension, n (%) 266 (50) 129 (46.7) 137 (53.7) 0.13 Filter clotting, n (%) 93 (17.5) 34 (12.3) 59 (23.1) 0.002 Hypokalemia, n (%) 60 (11.2) 32 (11.5) 28 (10.9) 0.93
Hypophosphataemia, 109 (20.5) 43 (15.5) 66 (25.8) 0.005 n (%) Use of anticoagulation, 219 (41.2) 125 (45.2) 94 (36.8) 0.06 n (%) Treatment 62 (11.6) 22 (79) 40 (15.6) 0.008 discontinuation, n (%) Values are presented in proportions.
Hypomagnesaemia and
hypophosphataemia are commonly concomitant and may also require replacement [1-3].
Refeeding syndrome manifests as severe
hypophosphataemia, hypoklaemia, hypomagnesaemia, fluid retention, and altered glucose homeostasis [11].
FGF23 inhibition of the reabsorption of tubular phosphate results in intermittent
hypophosphataemia, which occurs early on in CKD.
(1) CPPD can be linked to underlying metabolic disorders such as hemochromatosis, hyperparathyroidism,
hypophosphataemia, hypomagnesaemia and hypothyroidism, all of which increase the risk for calcium pyrophosphate deposition.
On the other hand, PTH promotes phosphorus renal elimination, and so hypophosphaturia and
hypophosphataemia are observed.
showed low rates of hypocalcemia, osteonecrosis, neutropenia,
hypophosphataemia, anemia, back pain, and pain in the extremities [20, 21].
These cruciferous plants were reported to be associated with
hypophosphataemia and haemoglobinuria due to their decreased phosphorous level, wider calcium to phosphorous ratio i.e.
