hypomelanosis of Ito

hy·po·mel·a·no·sis of I·to

[MIM*146150, MIM*308300, MIM*300337]
not a specific entity but rather represents features of many different forms of mosaicism; characterized by unilateral or bilateral hypopigmented macules in whorls, streaks, and patches in a "marble-cake" pattern, variably associated with epidermal nevi, alopecia, and ocular, skeletal, and neural abnormalities.
See also: incontinentia pigmenti.

hypomelanosis of Ito

Ito,

Minor, Japanese dermatologist, 1884-1982.
hypomelanosis of Ito - inherited hypopigmented macules variably associated with epidermal nevi, alopecia, and ocular, skeletal, and neural abnormalities. Synonym(s): incontinentia pigmenti achromians
Ito nevus - pigmentation of skin innervated by lateral branches of the supraclavicular nerve and the lateral cutaneous nerve of the arm.
References in periodicals archive ?
Other dermatoses observed in this study were Lichen striatus, Linear Lichen planus, inflammatory Linear verrucous epidermal nevus, Lichen nitidus, Paederus dermatitis, Hypomelanosis of Ito, Linear and Whorled nevoid hypermelanosis.
17 cases of Lichen striatus, 5 cases of Linear Lichen planus, 2 cases of inflammatory linear verrucous epidermal nevus, Paederus dermatitis, Lichen nitidus and 1 case of Hypomelanosis of Ito and Linear and whorled nevoid hypermelanosis were encountered.
The distribution and symmetry of the lines allow the differential diagnosis with entities such as hypomelanosis of Ito, incontinentia pigmenti, linear epidermal nevus and lichen striatus.
4 In some patients with hypomelanosis of Ito or piebaldism, acquired pigmented macules may occur.
Such enlargement of the PVS can also be seen in Lowe syndrome [5] and hypomelanosis of Ito.
Hypomelanosis of Ito presents as developmental delay plus swirls or patches of hypopigrnentation or depigmentation along the lines of Blaschko, Dr.
About half of the people with hypomelanosis of Ito will show chromosomal mosaicism, which means that there is more than one cell line in the chromosomes.
6%); hypomelanosis of Ito (7%); combined hyper- and hypopigmentation (7%); and nevus depigmentosus (3.
Structural changes of the brain were seen in about half of the patients with linear hyperpigmented bands, half of those with hypomelanosis of Ito, and in one of the children with incontinentia pigmenti.
We read with interest the article by Xu et al[1] reporting on the occurrence of a primary meningeal rhabdomyosarcoma in a 15-month-old boy with hypomelanosis of Ito (HI).
My 12-year-old daughter was diagnosed with hypomelanosis of Ito (a rare disorder characterized by an unusual lack of skin color affecting many areas of the body and associated with other symptoms, such as mental retardation, seizuresvisual and ocular defects, overgrowth of brain tissue, and/or a small head) at the age of 2 years.
Hypomelanosis of Ito ("incontinentia pigmenti achromians").