hypokalemic periodic paralysis


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Related to hypokalemic periodic paralysis: thyrotoxic periodic paralysis

hy·po·ka·le·mic per·i·od·ic pa·ral·y·sis

[type I MIM*170400]
a form of periodic paralysis in which the serum potassium level is low during attacks; onset usually occurs between the ages of 7-21 years; attacks may be precipitated by exposure to environmental cold, high carbohydrate meal, or alcohol, may last hours to days, and may cause respiratory paralysis; autosomal dominant caused by mutation in the muscle dihydropyridine (DHP)-sensitive calcium channel α-1-subunit (CACNL1A3) on chromosome 1q or X-linked inheritance.

hypokalemic periodic paralysis

Familial periodic paralysis, see there.

hy·po·ka·le·mic per·i·od·ic pa·ral·y·sis

(hī'pō-kă-lē'mik pēr'ē-od'ik păr-al'i-sis)
Periodic paralysis in which the serum potassium level is low during attacks; attacks may be precipitated by cold, high carbohydrate meals, or alcohol, may last hours to days, and may cause respiratory paralysis.
Synonym(s): hypokalaemic periodic paralysis.
References in periodicals archive ?
Surgical treatment for thyrotoxic hypokalemic periodic paralysis: case report.
In familial Hypokalemic periodic paralysis paradoxical depolarization is caused by mutations in the voltage sensor of Nav1.4 and Cav1.1 channels giving imbalance between inward leak current and outward K current.
In one series, tachycardia (mean heart rate = 105 bpm) was noted at presentation and distinguished these patients from those with familial hypokalemic periodic paralysis [22].
Skeletal muscle dihydropyridine-sensitive calcium channel (CACNA1S) gene mutations in Chinese patients with hypokalemic periodic paralysis. Am J Med Sci 2005; 329: 66-70.
Inadvertent iodine excess causing thyrotoxic hypokalemic periodic paralysis. Arch Intern Med 2005;165:2536; author reply 2536.
Hypokalemic periodic paralysis, characterized by a fall in potassium levels in the blood, was the first of the three types of periodic paralysis to be identified and studied.
Thyrotoxicosis and primary hyperaldosteronism both cause hypokalemic periodic paralysis. Thyrotoxic periodic paralysis is usually associated with Graves' disease (2).
M2 EQUITYBITES-August 11, 2015-Taro Pharmaceutical Industries wins US FDA approval for Keveyis 50 mg tablets for treating primary hyperkalemic and hypokalemic periodic paralysis
M2 PHARMA-August 11, 2015-Taro Pharmaceutical Industries wins US FDA approval for Keveyis 50 mg tablets for treating primary hyperkalemic and hypokalemic periodic paralysis
[3,4] Hypokalemic periodic paralysis, urolithiasis, or osteomalacia are uncommon renal manifestations of pSS.