hypokalemic periodic paralysis


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Related to hypokalemic periodic paralysis: thyrotoxic periodic paralysis

hy·po·ka·le·mic per·i·od·ic pa·ral·y·sis

[type I MIM*170400]
a form of periodic paralysis in which the serum potassium level is low during attacks; onset usually occurs between the ages of 7-21 years; attacks may be precipitated by exposure to environmental cold, high carbohydrate meal, or alcohol, may last hours to days, and may cause respiratory paralysis; autosomal dominant caused by mutation in the muscle dihydropyridine (DHP)-sensitive calcium channel α-1-subunit (CACNL1A3) on chromosome 1q or X-linked inheritance.

hypokalemic periodic paralysis

Etymology: Gk, hypo, under; L, kalium, potassium; Gk, peri, near, hodos, way, paralyein, to be palsied
a state of recurring attacks of muscular weakness associated with low blood levels of potassium.

hypokalemic periodic paralysis

Familial periodic paralysis, see there.

hy·po·ka·le·mic per·i·od·ic pa·ral·y·sis

(hī'pō-kă-lē'mik pēr'ē-od'ik păr-al'i-sis)
Periodic paralysis in which the serum potassium level is low during attacks; attacks may be precipitated by cold, high carbohydrate meals, or alcohol, may last hours to days, and may cause respiratory paralysis.
Synonym(s): hypokalaemic periodic paralysis.
References in periodicals archive ?
6 cause susceptibility to thyrotoxic hypokalemic periodic paralysis.
Thyrotopin secreting pituitary adenoma presenting as hypokalemic periodic paralysis.
Thyrotoxic hypokalemic periodic paralysis in a Native American patient: case report and literature review.
As indicated in the report by Laroia et al, (1) hypokalemic periodic paralysis can occur in Caucasians.
Thyrotoxic periodic paralysis has no familial tendency, unlike familial hypokalemic periodic paralysis.
Attacks are typically more frequent but shorter in duration than those of hypokalemic periodic paralysis.
2) Although there are reports of thyrotoxicosis presenting as hypokalemic periodic paralysis, it has not been described with amiodarone therapy.
Pharmaceutical company Taro Pharmaceutical Industries (NYSE:TARO) revealed on Monday the receipt of the US Food and Drug Administration's (FDA) approval for Keveyis (dichlorphenamide) 50 mg Tablets for the treatment of primary hyperkalemic and hypokalemic periodic paralysis.