Elderly patients exhibit a weakened condition of body function, which may result in multiple organ failure when there was a hypohepatia
These would attribute to the reduction of hepatocyte microsomal enzyme activity, hypohepatia
, and renal insufficiency in the elderly.
Excessive hepatocyte apoptosis is bound to induce hypohepatia
in damaged liver.
A number of changes may occur in the intestinal mucosa and hepatocytes after acute intestinal I/R, leading to intestinal barrier dysfunction, bacterial translocation, systemic inflammation, and accompanying hypohepatia
[8, 9, 11, 12].
However, the majority of HCC patients usually have cirrhosis and hypohepatia
. Because of this, hepatectomy increases the risk of developing significant postoperative complications including ascites, hepatic failure, encephalopathy, and portal vein thrombosis .