hypogonadotropic


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Related to hypogonadotropic: Kallmann syndrome, hypogonadotropic amenorrhea

hypogonadotropic

 [hi″po-gon″ah-do-trōp´ik]
relating to or caused by deficiency of gonadotropin.

hy·po·gon·a·do·trop·ic

(hī'pō-gon'ă-dō-trop'ik),
Indicating inadequate secretion of gonadotropins and its consequences.

hypogonadism

Endocrinology
1. Inadequate gonadal function, as manifest by defects in gametogenesis, secretion of, and/or response to, gonadal hormones. Cf Androgen replacement therapy.
2. A clinical condition with ↓ or absent phenotypic expression of a person's sexual genotype, which may be 1º, due to a lack of end organ response to FSH or LH produced normally by an intact pituitary gland–hypergonadotropic hypogonadism, or 2º to defective hypothalamic or pituitary hormonal activity–hypogonadotropic hypogonadism
Hypogonadism, etiology
Primary
Hypergonadotropic Turner syndrome, XX Turner sydrome, XX pure gonadal dysgenesis, mixed gonadal dysgenesis, autoimmune ovarian disease
Hypergonadotropic Congenital anorchia, rudimentary testes, germ cell hypoplasia–del Castillo syndrome, XY Turner phenotype–Noonan syndrome, Klinefelter syndrome and variants, XX males, XYY males
Secondary
Hypogonadotropic Carpenter syndrome, hypopituitarism, Lawrence-Moon-Biedl, multiple lentigines syndrome, polycystic ovaries
Hypogonadotropic Amyloidosis, Carpenter syndome, fertile eunuch syndrome, Fröhlich syndrome, Sheehan syndrome, Kallmann's disease, Laurence-Moon-Biedl disease, Lowe syndrome, Prader-Willi syndrome  
.

hy·po·gon·a·do·tro·pic

(hī'pō-gon'ă-dō-trō'pik)
Indicating inadequate secretion of gonadotropins and its consequences.
References in periodicals archive ?
Two novel missense mutations in G protein-coupled receptor 54 in a patient with hypogonadotropic hypogonadism.
Congenital hypogonadotropic hypogonadism and micropenis: effect of testosterone treatment on adult penile size why sex reversal is not indicated.
Prevalence, phenotypic spectrum, and modes of inheritance of gonadotropin-releasing hormone receptor mutations in idiopathic hypogonadotropic hypogonadism.
High levels of serum-estradiol suppressed secretion of luteinizing and follicle-stimulating hormone due to negative feedback and caused hypogonadotropic hypogonadism which resolved after surgery (Table 1).
Balercia, "Effects of testosterone replacement therapy on bone metabolism in male post-surgical hypogonadotropic hypogonadism: focus on the role of androgen receptor CAG polymorphism," Journal of Endocrinological Investigation, vol.
Insulin Resistance and Inflammation in Hypogonadotropic Hypogonadism and Their Reduction After Testosterone Replacement in Men With Type 2 Diabetes.
In June 2015, the FDA announced that "testosterone treatment is indicated for replacement therapy only in males with conditions associated with a deficiency in endogenous testosterone, specifically primary hypogonadism or hypogonadotropic hypogonadism" [5].
GnRH agonists have a direct action on the pituitary, inducing downregulation and desensitization of the GnRH receptors, producing a hypogonadotropic state with consequent reduction in estradiol and progesterone [16].
Primary (or hypogonadotropic) hypogonadism results when the testes fail to produce adequate testosterone in the presence of normal serum luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels.
Global Markets Direct's, 'Secondary (Hypogonadotropic) Hypogonadism - Pipeline Review, H1 2016', provides an overview of the Secondary (Hypogonadotropic) Hypogonadism pipeline landscape.
However, the temporary change to hypogonadotropic hypogonadism takes place as soon as 2-3 weeks with return of circulating sex steroids to normal range within 6 months after successful renal transplantation [11].
Background: Delayed puberty can result either from constitutional delay of growth and puberty (CDP) or idiopathic hypogonadotropic hypogonadism (IHH).