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Related to hypogonadotropic: Kallmann syndrome, hypogonadotropic amenorrhea


relating to or caused by deficiency of gonadotropin.


Indicating inadequate secretion of gonadotropins and its consequences.


/hy·po·go·nado·tro·pic/ (-go-nad″ah-tro´pik) relating to or caused by deficiency of gonadotropin.


1. Inadequate gonadal function, as manifest by defects in gametogenesis, secretion of, and/or response to, gonadal hormones. Cf Androgen replacement therapy.
2. A clinical condition with ↓ or absent phenotypic expression of a person's sexual genotype, which may be 1º, due to a lack of end organ response to FSH or LH produced normally by an intact pituitary gland–hypergonadotropic hypogonadism, or 2º to defective hypothalamic or pituitary hormonal activity–hypogonadotropic hypogonadism
Hypogonadism, etiology
Hypergonadotropic Turner syndrome, XX Turner sydrome, XX pure gonadal dysgenesis, mixed gonadal dysgenesis, autoimmune ovarian disease
Hypergonadotropic Congenital anorchia, rudimentary testes, germ cell hypoplasia–del Castillo syndrome, XY Turner phenotype–Noonan syndrome, Klinefelter syndrome and variants, XX males, XYY males
Hypogonadotropic Carpenter syndrome, hypopituitarism, Lawrence-Moon-Biedl, multiple lentigines syndrome, polycystic ovaries
Hypogonadotropic Amyloidosis, Carpenter syndome, fertile eunuch syndrome, Fröhlich syndrome, Sheehan syndrome, Kallmann's disease, Laurence-Moon-Biedl disease, Lowe syndrome, Prader-Willi syndrome  


Indicating inadequate secretion of gonadotropins and its consequences.


relating to or caused by deficiency of gonadotropin.
References in periodicals archive ?
The report reviews key players involved in the therapeutics development for Hypogonadotropic Hypogonadism and enlists all their major and minor projects
Mutation Ala(171)Thr stabilizes the gonadotropins-releasing hormones receptor in its inactive conformation, causing familiar hypogonadotropic hypogonadism.
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54.
AMH has been examined in numerous studies and is an established ovarian marker for poor response to in vitro fertilisation, polycystic ovary syndrome, hypogonadotropic hypogonadism and also age at menopause.
Maintenance of sexual function with testosterone in the gonadotropin-releasing hormone-immunized hypogonadotropic infertile male rat.
Regarding the group with a defined diagnosis, androgen receptor defects (n = 25), 5[alpha]-reductase type 2 deficiency (n = 20), and hypogonadotropic hypogonadism (n = 12), including six with associated hypopituitarism, were found with higher frequencies, followed by the group of defects in testosterone synthesis that included one patient with HSD3B2 deficiency, one with CYP17A1 deficiency, and two with HSD17B3 deficiency.
Background: Delayed puberty can result either from constitutional delay of growth and puberty (CDP) or idiopathic hypogonadotropic hypogonadism (IHH).
Adult-onset hypogonadotropic hypogonadism caused by aberrant expression of aromatase in an adrenocortical adenocarcinoma.
The company's initial portfolio consists of clinical-stage products acquired from Novartis to treat brittle bone syndrome, acute exacerbations of chronic obstructive pulmonary disease, and hypogonadotropic hypogonadism.
21) indicated that among the living BT patients over the age of 15, hypogonadotropic hypogonadism, HCV infection, diabetes, heart failure, and arrhythmia are the common complications.
In familial hypogonadotropic hypogonadism, mutations of neurokinin B gene and its respective receptor TACR3 suggested an eventual key role for neurokinin B in the central control of reproduction [17].