hypochromic effect

hy·po·chro·mic ef·fect

a phenomenon in which an individual molecule, containing several chromophores, has a certain absorptivity (or optic density) at a given wavelength that is less than the sum of the optic densities of the individual chromophores (at that same wavelength).

hypochromic effect

the decrease in the absorbance of UV (∼260 nm) that accompanies the denaturation (melting) of DNA and used to monitor the process.
References in periodicals archive ?
Secondly, the alkaline extract exerted a marked hypochromic effect on the yellow chromogen, again minimizing interference without the need to include a correction factor.
The self-organization of adenosine 5'-triphosphate and adenosine 5'-diphosphate in aqueous solution as determined from ultraviolet hypochromic effects.