Rather than hypercholesterolemia in high risk patients, we have found hypocholesterolemia
HDL to be very high in our study population and this was the most common abnormality found in 44.3% of the patients.
is associated negatively with hemolysate lipid peroxidation in sickle cell anemia patients," Clinical and Experimental Medicine, vol.
Chen, "Primary and secondary hypocholesterolemia
," Beijing Da Xue Xue Bao, vol.
--Other factors like heavy alcohol use, hypocholesterolemia
(< 150 mg/dl cholesterol) -(3 cases; 2%)
Adjusting age and with further segregation of total cholesterol levels into seven groups in a univariate general linear model showed higher mean platelet volume at both extremes of cholesterol i.e., hypocholesterolemia
(less than 4.5 mmol/L) and hypercholesterolemia (greater than 6.0 mmol/L).
Hu et al., "Hypocholesterolemia
of Rhizoma Coptidis alkaloids is related to the bile acid by up-regulated CYP7A1 in hyperlipidemic rats," Phytomedicine, vol.
Bisht et al., "Reduced circulating oxidized LDL is associated with hypocholesterolemia
and enhanced thiol status in Gilbert syndrome," Free Radical Biology and Medicine, vol.
Altered high density lipoprotein metabolism in patients with myeloproliferative disorders and hypocholesterolemia
(1993) reported that oral administration of TFG seed extract (10 and 100 mg/day per 300 g body weight) enhanced feed intake with motivation to eat in rats and also induced hyperinsulinemia and hypocholesterolemia
. Petit et al.
The present study showed no significant correlation between serum Mn and lipid profile parameters in the two groups, although another study has demonstrated that Mn enhanced cholesterol synthesis in the liver and hypocholesterolemia
has been reported in a human case of Mn deficiency; (26) however, the cause of this finding is probably due to no significant difference in Mn between the two groups.
Breslow et al16 pointed out poor nutritional status, weight loss, depletion of the triceps skinfold, hypoalbuminemia, hypocholesterolemia
and low levels of hemoglobin/hematocrit as independent risk for development of PU.
leads to non-detoxification of endotoxins and lipopolysaccharides resulting in metabolic syndrome x, neuronal degnerations and autoimmune disease [10-17].