However, a growing body of evidence indicates that comorbidities such as hypoalbuminemia
, cardiovascular disease, anemia, hypertension, and secondary hyperparathyroidism may be preventable or modifiable if addressed early in the renal function deterioration process, and may impact the rate of progression to ESRD and/or quality of life.
Cryptogenic multifocal ulcerous stenosing enteritis is a rare idiopathic cause of ulceration and stricture of small bowel, which can be presented with acute or chronic GI bleeding, symptoms of bowel obstruction, abdominal pain, anemia, hypoalbuminemia
, and perforation (1-5).
Several studies have shown that serum hypoalbuminemia
can be an independent risk factor for decreased microperfusion and pressure ulcers because albumin helps maintain oncotic pressure and vascular refilling [22-24].
is the prominent factor in post operative congenital heart disease patients.
Serum albumin was done in 25 out of 71 patients; 80% of the patients had hypoalbuminemia
, while only 20% pts.
was seen in 28 (56%) patients before treatment and 2 (4%) patients after treatment which was found to be statistically significant (pless than 0.05).
Breslow et al16 pointed out poor nutritional status, weight loss, depletion of the triceps skinfold, hypoalbuminemia
, hypocholesterolemia and low levels of hemoglobin/hematocrit as independent risk for development of PU.
* Check serum albumin levels of all patients at risk for hypoalbuminemia
; levels <35 g/L are strongly associated with postoperative pulmonary complications.
Concomitant factors include smoking (Waqar et al., 2005), steroid use (Hahler, 2006; Riou et al, 1992; Sorensen et al., 2005), obesity, malnutrition, anemia, hypoproteinemia, hypoalbuminemia
, uremia, wound infection, type of incision, and technique of wound closure (Eke & Jebbin, 2006).
Remarkable laboratory findings were: leukocytosis (mean white blood cells 18,400 cells/mcL); anemia (mean hemoglobin 10.4 g/dL); and hypoalbuminemia
(mean albumin 2.0 g/dL).
While it's known that NSAIDs are associated with small-intestine injuries and may be the cause of unexplained hypoalbuminemia
or anemia, the extent of the small-intestine damage had previously not been well characterized, according to the lead investigator, David Y.
Pregnancy and hypoalbuminemia
at the time of hospitalization were the only two independent factors related to the presence of renal scars at a mean of about 17 years follow-up.