Moreover, animals with brain lesions in this circuitry develop a hypoactivity
frame due to the extinction of the positive reinforcement for exercise (73).
Furthermore, decreased striatal inhibitory activity on the external part of the globus pallidus (GPe) results in increased inhibitory activity of the GPe, which in turn results in overinhibition of the subthalamic nucleus leading to hypoactivity
of the GPi.
Moreover, prominent hypoactivity
has been reported in cholinergic pathways in PD (40).
a) Clinical Bloodstream Infection--at least one of clinical signs (thermal instability, apnea, bradycardia, food intolerance, worsening respiratory distress, glucose intolerance, hemodynamic instability, and hypoactivity
or lethargy) AND all of following criteria: hemogram with three altered parameters or increased C-Reactive protein; not performed or negative blood culture; no evidence of infection at another site; antimicrobial therapy initiated or sustained by the attending physician.
Family and twin studies confirm that chronic insomnia can have a genetic component (heritability coefficients between 42% and 57%), whereas the investigation of autonomous and central nervous system parameters has identified hyperarousal as a final common pathway of the pathophysiology, implicating an imbalance of sleep-wake regulation consisting of either overactivity of the arousal systems, hypoactivity
of the sleep-inducing systems, or both.
16) Dopamine hypoactivity
has been widely accepted as a hypothesis for the occurrence of NMS.
, and an unwillingness to eat solid foods.
The cause of delayed hatchings demonstrated by the experimental groups could have been the hypoactivity
and motor dysfunction induced by central nervous system damage.
A PET scan is significant for hypoactivity
in the temporal and parietal lobes but, again, the images are interpreted as unremarkable overall.
There are emphasized the dysfunctional attitudes in imagining the future with the serotoninergic hypoactivity
of the prefrontal cortex, a hypoactivity
manifested clinically by despair, inhibited behaviour, insecurity and anxiety under adverse and stressful conditions.
On neurological examination, he had open consciousness, interest for the surroundings, hypotonia, hypoactivity
and decreased deep tendon reflexes.
Neuropathic mechanisms that might be at work in PIFP include nociceptor sensitization, phenotypic changes and ectopic activity from the nociceptors, central sensitization possibly maintained by ongoing activity from initially damaged peripheral tissues, sympathetic abnormal activity, alteration of segmental inhibitory control, or hyperactivity or hypoactivity
of descending controls.