hypervitaminosis A


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vitamin A poisoning

A potentially fatal condition evoked by an acute or chronic excess of vitamin A (> 20,000 IU) for more than two weeks.

Clinical findings
Bone pain, dry skin, gastrointestinal complaints (nausea, vomiting, constipation, diarrhoea), increased intracranial pressure, poor growth in children; affected infants may develop bulging fontanelles, craniotabes (softening of skull bones), pseudotumour cerebri, papilledema, drowsiness, severe headaches, insomnia, jaundice, menstrual disorders, stress, weight loss, irritability, decreased appetite, pruritis, hair loss, seborrhoea, and cracking at corners of mouth.

hypervitaminosis A

Vitamin A toxicity, see there.
References in periodicals archive ?
Hypervitaminosis A; experimental induction in the human subject.
A lethal hypervitaminosis A syndrome in young monkeys (Macacus fascicularis) following a single intramuscular dose of a water-miscible preparation containing vitamins A, D2 and E.
Acute hypervitaminosis A of the infant; its clinical manifestation with benign acute hydrocephalus and pronounced bulge of the fontanel; a clinical and biologic study.