Out of 107 hyperuricaemic patients of hypertensive group 39% patients developed hypertensive retinopathy while only 24% patients developed hypertensive retinopathy of normouricaemia group.
Hyperuricaemic patients significantly developed more hypertensive retinopathy in comparison to normouricaemic patients (* p<0.02; ** chi square test).
Genome-wide study of familial juvenile hyperuricaemic
(gouty) nephropathy (FJHN) indicates a new locus, FJHN3, linked to chromosome 2p22.1-p21.
In a key article, Kang and Nakagawa  stated that experimental data using hyperuricaemic
animals and cultured cells provide robust evidence regarding hypertension, proteinuria, vascular disease and progressive renal scaring.
About 10% of people with hyperuricemia develop gout and 90% of patients with gout are hyperuricaemic
Familial juvenile hyperuricaemic
nephropathy (FJHN): linkage analysis in 15 families, physical and transcriptional characterisation of the FJHN critical region on chromosome 16p11.2 and the analysis of seven candidate genes.
Age in Years High Normal Uric Acid Uric Acid Present Study 59.55 58.16 Agarwal S et al (13) 60.59 58.90 The mean ages in hyperuricaemic
population and in normouricaemic population were 59.55 years, 58.16 years respectively in this study.
hypertension' has in small studies been shown to be reversible with urate-lowering therapy, at least in the early stages, i.e.
Functional consequences of a novel uromodulin mutation in a family with familial juvenile hyperuricaemic
Thus DM-II is a normouricaemic state with hyperuricaemic
tendency and this level of hyperuricaemia act as additional risk factor for CAD.
patients frequently suffer from kidney disorders and vice versa, and stages 4-5 CKD patients tend to have hyperuricaemia.
Inhibition of adjuvant-induced arthritis in the Hyperuricaemic