Comparison of the effects of 7.2% hypertonic saline
and 20% mannitol on whole blood coagulation and platelet function in dogs with suspected intracranial hypertension - a pilot study.
Conclusion: Hypertonic saline
resulted in significant reductions in modified respiratory assessment score (MRAS) and hospital stay as compared to normal saline in children with acute bronchiolitis.
Further, an unexpected finding was that corticomotor excitability of the FDI muscle returned to baseline within 10 min after hypertonic saline
injection, whereas previous studies have shown prolonged reduction of MEPs.
In GUERANDE, infants with a first episode of acute bronchiolitis were given two 20-minute nebulizations of 3% hypertonic saline
or 0.9% normal saline 20 minutes apart.
(9) reported that out of 2105 patients in whom hypertonic saline
was injected to manage pain, 1% developed paraplegia or quadriplegia.
If hyponatraemia (serum sodium <135 mmol/L) can be demonstrated in the field, oral or IV hypertonic saline
(100 mL 3% NaCl) can be administered every 10 minutes until 3 doses have been completed or neurological symptoms improve.'91 An oral mixture of hypertonic saline
can be created by adding 3-4 stock cubes to half a cup of water.
Care was taken to avoid spillage of cystic fluid and after cystectomy, the dead space was irrigated with hypertonic saline
as scolicide for fear of accidental spillage.
resuscitation reduces apoptosis and tissue damage of the small intestine in a mouse model of hemorrhagic shock.
The efficacy of hypertonic saline
(HTS) in reducing ICP has been shown in multiple animal and human studies in various conditions such as traumatic brain injury, subarachnoid hemorrhage, acute ischemic stroke, brain tumors, and acute hepatic failure.
reported two and three cases, respectively, of chronic parotid fistulae treated through hypertonic saline
injections.[sup], These injections were used to induce conformational denaturation of cell membrane proteins in situ , and saline could be diluted below the level of cellular toxicity.
While hospitalization length was not effected from receiving inhaled bronchodilator, ipratropium bromide or hypertonic saline
, the duration was longer in patients receiving inhaled corticosteroid when compared with patients who didn't receive inhaled corticosteroid.
After 5 min, 10 mL of 10% hypertonic saline
was slowly injected under real-time fluoroscopic guidance while frequently asking the patient to describe any newly developed symptoms.