hyperthyroxinemia


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thyroxine

 (T4) [thi-rok´sin]
a thyroid hormone that contains iodine and is a derivative of the amino acid tyrosine, occurring naturally as l-thyroxine; its chemical name is tetraiodothyronine. It is formed and stored in the thyroid follicles as thyroglobulin and released from the gland by the action of a proteolytic enzyme. It is deiodinated in peripheral tissues to form triiodothyronine (T3), which has a greater biological activity.



Thyroxine acts as a catalyst in the body and influences a great variety of effects, including metabolic rate (oxygen consumption); growth and development; metabolism of carbohydrates, fats, proteins, electrolytes, and water; vitamin requirements; reproduction; and resistance to infection. Pharmaceutical preparations of thyroxine, extracted from animals or made synthetically, are called levothyroxine.
free thyroxine the fraction of thyroxine in the serum that is not bound to a binding protein.

hy·per·thy·rox·i·ne·mi·a

(hī'pĕr-thī-rok'si-nē'mē-ă),
An elevated thyroxine concentration in the blood.

hy·per·thy·rox·i·ne·mi·a

(hī'pĕr-thī-rok'si-nē'mē-ă)
An elevated thyroxine concentration in the blood.
Synonym(s): hyperthyroxinaemia.

hyperthyroxinemia

an excess of thyroxine in the blood.
References in periodicals archive ?
Early in the course of the hyperthyroxinemia, it may not be possible to differentiate transient from persistent disease.
4], free thyroxine; FDH, familial dysalbuminemic hyperthyroxinemia.
7) first described familial euthyroid hyperthyroxinemia attributable to a mutant TTR with increased [T.
These findings confirmed the diagnosis of dysprealbuminemic hyperthyroxinemia.
Familial dysalbuminemic hyperthyroxinemia and thyroid hormone autoantibodies: interterence in current free thyroid hormone assays.
4] and TSH values in our study might be attributable in part to transient hyperthyroxinemia that did not last long enough to induce a decrease in TSH to <0.
Euthyroid familial hyperthyroxinemia due to abnormal thyroid hormone binding protein.
A point mutation in the human serum albumin gene results in familial dysalbuminemic hyperthyroxinemia.
All patients had normal concentrations of thyroid-binding globulin, a negative screen for familial dysalbuminemic hyperthyroxinemia, and no anti-[T.