Oil Immersion View of
Hypersegmented Neutrophil in Peripheral Smear (Leishman Stain 100 x 10X)
Peripheral blood smear revealed an abundance of schistocytes and occasional
hypersegmented neutrophils (see Figures 3 and 4).
Bahitz et al., "
Hypersegmented neutrophils and vitamin B12 deficiency.
The differential shows 39 percent
hypersegmented neutrophils, and the white blood cell count is slightly decreased.
Hypersegmented neutrophils were seen in aspiration smear (Figure 2c).
Patients with Peripheral smear showing predominant macrocytes,
hypersegmented neutrophils, and clinical features suspected of megaloblastic anemia; like knuckle pigmentation, early graying of hair, dyspepsia, bald tongue along with anemia, proven B12 deficiency biochemically and bone marrow proven megaloblastic anemia were included in the study.
It is a rapidly correctable disorder and should be promptly notified.M
Hypersegmented neutrophils were noted in 60% compared to 84.9% of cases in Tilak V et al in megaloblastic anemia.
Total WBC count was found subnormal in about 60% of the patients, thrombocytopenia (26%), and
hypersegmented neutrophils (14%).
Peripheral blood smear showed normocytic hypochromic red blood cells with
hypersegmented neutrophils, severe thrombocytopenia.