hyperreactive malarious splenomegaly

hy·per·re·ac·tive ma·lar·i·ous sple·no·meg·a·ly

a syndrome characterized by persistent splenomegaly, exceptionally high serum IgM and malaria antibody levels, and hepatic sinusoidal lymphocytosis; believed to be a disturbance in the T-lymphocyte control of the humoral response to recurrent malaria.

hy·per·re·ac·tive ma·lar·i·ous sple·no·meg·a·ly

(hī'pĕr-ak'tiv mă-lar'ē-ŭs splē'nō-meg'ă-lē)
A syndrome characterized by persistent splenomegaly, exceptionally high serum IgM and malaria antibody levels, and hepatic sinusoidal lymphocytosis.
Synonym(s): tropical splenomegaly syndrome.

hy·per·re·ac·tive ma·lar·i·ous sple·no·meg·a·ly

(hī'pĕr-ak'tiv mă-lar'ē-ŭs splē'nō-meg'ă-lē)
Syndrome characterized by persistent splenomegaly, exceptionally high serum IgM and malaria antibody levels, and hepatic sinusoidal lymphocytosis.
References in periodicals archive ?
Hyperreactive malarious splenomegaly (HMS), known as Tropical Splenomegaly Syndrome, (1) despite being common in malaria-endemic regions and in travelers from non-endemic areas, (2) has low prevalence in Brazil.
Recent studies of hyperreactive malarious splenomegaly (tropical splenomegaly syndrome) in Papua New Guinea.
HLA heterozygosity and hyperreactive malarious splenomegaly in the Upper Watut Valley of Nova Guinea.
IGHG3 G and the pathogenesis of hyperreactive malarious splenomegaly.