where macroprolactinoma was the dominant lesion.10 It is important to differentiate between non-function pituitary adenomas with hyperprolactinemia
due to stalk effect and true macroprolactinoma.
Macroprolactinemia is a neglected cause of hyperprolactinemia
in cases with unexplained etiology.
Lactotroph pituitary adenomas, also called prolactinomas, account for almost half of non-physiologic hyperprolactinemia
. Other pituitary adenomas which not secrete prolactin may also cause hyperprolactinemia
by compression of the pituitary stalk.
: physiopathology, clinical features and guidance.
Results: A total of 35 patients (58.33%) developed hyperprolactinemia
. The olanzapine group showed 13 out of 30 patients (43.33%) and risperidone group showed 22 out of 30 patients (73.33%) with raised prolactin levels with p-value of 0.018 indicating that the difference was statistically significant.
The drug induced underactivity of dopamine in Tuberinfundibular pathway causes Hyperprolactinemia
in which Prolactin is released more than normal.
Adjunctive metformin for antipsychotic-induced hyperprolactinemia
: A systematic review.
, women won't conceive because the body is acting as if it's in a lactation stage.
If the patient later develops hyperprolactinemia
, having a baseline measurement will make it easier to determine if the antipsychotic is a potential cause.
Major proportion of infertile females presented with PCOS and hyperprolactinemia
; followed by premature ovarian failure, hirsuitism and resistance ovarian syndrome, respectively (Figure 2).
Another 25 percent of the new awards fund studies evaluating drug products for rare endocrine disorders, including Cushing disease, dopamine agonist intolerant hyperprolactinemia
and congenital adrenal hyperplasia.
Erectile dysfunction (ED) is defined by the consistent or recurrent inability to attain or maintain penile erection adequate for sexual intercourse.1 Epidemiological studies have suggested that more than 30 million males in United States are affected by ED.2 QJ Zhang and his colleagues reported that the prevalence of ED is 26.1% in the three major cities of Beijing, Chongqing and Guangzhou in China.3 Penile erection is a complex process involving psychogenic and hormonal input.4 Endocrine disorders, hypogonadism, hyperprolactinemia
and thyroid diseases, are common risk factors of ED.5,6 Previous studies have reported that in overt hypothyroidism, the ratio of ED reach up to 52.1% and moreover overt thyroid function failure adversely affects erectile function among males.7,8