Other gastric polyps, including
hyperplastic polyp and fundic gland polyp, are less likely in the differential because these are predominantly "mucosal-based" polyps.
The proportions of
hyperplastic polyp (HP), sessile serrated adenoma/polyp (SSA/P), and traditional serrated adenoma (TSA) of all serrated polyps were 41.
A
hyperplastic polyp may not change the screening interval, whereas a tubulovillous adenoma may require a repeat colonoscopy in less than a year.
The characteristic microscopic feature of a
hyperplastic polyp is the serrated or saw-tooth configuration of the crypt epithelium.
8 were investigated with colonoscopy and this group had 13 cancers, eight adenomas and one
hyperplastic polyp.
Distinguishing between
hyperplastic polyp, sessile serrated adenoma, and traditional serrated adenoma is not only very challenging, the distinctions have important clinical implications.
1 patient had a
hyperplastic polyp and 1 patient had a lipoma.
Two German pathologists, Feyrter in 1929 (3) and Westhues in 1934, (4) are credited as being the first to use the term
hyperplastic polyp in German-language literature.
Currently, 3 types of serrated polyps are acknowledged in the fourth edition (2010) of the World Health Organization (WHO) Classification of Tumors of the Digestive System (18):
hyperplastic polyp (HP), sessile serrated adenoma/polyp (SSA/P), and traditional serrated adenoma (TSA).
6-8,20) The serrated polyp family members include the microvesicular
hyperplastic polyp, goblet cell-rich
hyperplastic polyp, traditional serrated adenoma, filiform serrated adenoma, and SSA/P.
One does not assign different RVUs to a colon biopsy that is positive for malignancy and one that shows a
hyperplastic polyp because one diagnosis has more important implications than the other.
In two-thirds of the cases, the trapped crypts have serrated architecture, so they have an appearance identical to the crypts in a
hyperplastic polyp (Figure 2, B).
