They share similar morphologic features with both the conventional adenoma and the
hyperplastic polyp in a fashion that is different from a mixed adenoma and a
hyperplastic polyp.
3) In this article, we describe a case of colchicine effect in a colonic
hyperplastic polyp that mimicked the appearance of a serrated adenoma and that occurred in a patient receiving a nontoxic dose of colchicine.
This description suggests that these cells show absorptive enterocyte differentiation, thus we may still consider their polyp to be a
hyperplastic polyp with absorptive enterocyte differentiation having mixed components of tubular and villous adenomatous glands and, in addition, a focus of high-grade dysplasia.
One or more polyps were found in 49% of the participants, including 32% with an adenoma or
hyperplastic polyp, 23% with any adenoma, and 6% with an advanced adenoma.
According to the guidelines, the finding of a
hyperplastic polyp on screening colonoscopy is a low-risk situation that doesn't warrant stepped-up surveillance; the recommendation is for an affected patient to undergo subsequent colonoscopy at the standard 10-year screening interval.
Among those who perform screening colonoscopy, 24% of the gastroenterologists and 54% of the general surgeons said they would recommend surveillance colonoscopy after finding a
hyperplastic polyp.
But "it is becoming clear that there is a second type of
hyperplastic polyp that appears similar histologically but is large, located in the proximal colon, and genetically distinct, and may have subtle morphologic distinctions.
In two-thirds of the cases, the trapped crypts have serrated architecture, so they have an appearance identical to the crypts in a
hyperplastic polyp (Figure 2, B).
An adenomatous polyp is a benign, precancerous growth that, if not removed, has the greatest risk of becoming cancer; a
hyperplastic polyp is a benign growth with no potential to develop into cancer.
Adenocarcinoma arising from a
hyperplastic polyp with adenomatous foci.
Overall, screening found 91
hyperplastic polyps, 79 of which were tubular adenoma.
Of these small polyps, about 70% were clinically insignificant, representing either normal colon or
hyperplastic polyps.
