Why is the hyperplastic polyp
a marker for precancerous condition of the gastric mucosa.
Histopathology, Immunohistochemistry, and Molecular Characteristics.--Most duodenal hyperplastic polyps
reported so far in the literature (14 of 16 cases; 87.5%) have the histologic appearance of a microvesicular hyperplastic polyp
of the large bowel, characterized by hyperplastic, columnar microvesciular mucinous epithelium with luminal and crypt serration lacking cytologic atypia (Figure 4, A).
KEYWORDS: Clinical and Pathological Features, Colorectal Serrated Polyps, Hyperplastic Polyp
, Sessile Serrated Adenoma/Polyp.
Microscopic examination of the nonadenomatous polyps (n=27) led to a variety of findings duodenitis/inflammatory polyp (n=10), normal duodenal tissue (n=7), gastric heterotopia (n=4), Brunner's gland hyperplasia (n=2), hyperplastic polyp
(n=1), leiomyoma (n=1), lipoma (n=1), and vascular ectasia consistent with portal hypertensive duodenopathy (n=1).
Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp
and sessile serrated polyp/adenoma.
Serrated lesions were categorized as hyperplastic polyp
, sessile serrated adenoma and traditional serrated adenoma.
Regarding serrated polyps, there are three types of polyps such as hyperplastic polyp
, traditional serrated adenoma (TSA), and SSA/P .
Biopsy of the stricture was taken which proved pathologically to be a benign hyperplastic polyp
On the other hand, we present three cases that I know my colleagues read with interest and which never lose their popularity: hyperplastic polyp
of the appendix, traumatic sigmoid colon perforation, and endoscopic removal of a foreign body in a rare and intriguing patient with situs inversus totalis.
Its concomitant occurrence with hyperplastic polyp
has never been reported.
The proportions of hyperplastic polyp
(HP), sessile serrated adenoma/polyp (SSA/P), and traditional serrated adenoma (TSA) of all serrated polyps were 41.2%, 7.2%, and 51.6%, respectively, which showed a lower proportion of HP and SSA/P and a higher proportion of TSA.
These diagnoses included the following: melanosis coli (in 4 specimens with tubular adenomas and 1 specimen with hyperplastic polyp
), mucosal prolapse (in 2 specimens with hyperplastic polyps
), schistosomiasis (Figures 4(a), 4(b), and 4(c)) (in 1 specimen with adenocarcinoma and 1 specimen with hyperplastic polyp
), and intestinal spirochetosis (Figure 5) (in 1 specimen with sessile serrated adenoma), and they were confirmed retrospectively by both of us.