, hypocalcaemia, hypercalcaemia, elevated calcium-phosphate product (CaXP) and elevated ALP.
Disorders that are implicated in the pathogenesis of calciphylaxis include chronic renal failure, obesity, hypercalcaemia, hyperphosphataemia
, hypothyroidism, hyperparathyroidism and perhaps a variety of hypercoaguable states.
Hypocalcaemia is frequently associated with hyperphosphataemia
in CKD with its mechanism associated with primary hyposecretion of parathormone which results in a progressive decrease in blood calcium levels up to a steady state characterised by an equality between urinary calcium excretion and osseous calcium secretion [13,14].
Sevelamer for hyperphosphataemia
in kidney failure: Controversy and perspective.
and phosphate binders in chronic kidney disease.
Cozzolino M, Mazzaferro S, Brandenburg V: The treatment of hyperphosphataemia
in CKD: Calciumbased or calcium-free phosphate binders?
was associated with 53% of hypocalcemic patients (Hypoparathyroidism was suspected in 26 patients).
Unlike in this study, hyperphosphataemia
used to indicate bone disorder was found in 28-40% of patients undergoing PD (Badve & McCorrmck, 2008; Dong et al.
Electrolyte abnormalities such as hyperkalaemia, hyperphosphataemia
and hypocalcaemia occur, but are not specific enough for diagnostic certainty.
Side-effects of intravenous phosphate repletion are hypocalcaemia, metastatic calcification, hyperkalaemia (which is associated with potassium-containing supplements), volume excess, metabolic acidosis, and hyperphosphataemia
Life threatening hyperphosphataemia
after administration of sodium phosphate in preparation for colonoscopy.
Based on biochemical and hormonal investigations, cases of bent leg syndrome were etiologically grouped into four categories as bent leg owing to either hypovitaminosis-D (group A), secondary nutritional hyperparathyroidism (group B), high calcium supplementation (group C) or hyperphosphataemia