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A drug that makes blood plasma hypertonic thus drawing fluid out of the eye and leading to a reduction in intraocular pressure. It is used in solution in the treatment of angle-closure glaucoma and sometimes before surgery to decrease the intraocular pressure. Common agents include glycerin (glycerol), isosorbide, mannitol and urea. See hypertonic solution.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann