hyperlipidaemia

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hyperlipidaemia

An abnormal increase in the levels of fats (lipids), including cholesterol, in the blood. This may be of dietary origin or may be due to PANCREATITIS or bile system disorder or may be a dangerous familial disorder of dominant inheritance. Most people with familial hyperlipidaemia develop serious coronary artery disease before the age of 50.

hyperlipidaemia

an abnormally elevated plasma lipid level. A significant risk factor for coronary artery disease (ischaemic heart disease) which can be familial or acquired (largely through lifestyle, especially high-fat diet). The condition is asymptomatic and only diagnosed by a screening blood test or following a cardiac event. While treatment requires dietary modification, newer lipid-lowering drugs (statins) have led to much better results and a reduction in morbidity and mortality. See also cholesterol, lipids.

hyperlipidaemia

raised levels of total blood lipids (i.e. >10 g/dL)

hy·per·lip·id·e·mi·a

(hī'pĕr-lip'i-dē'mē-ă)
Elevated levels of lipids in the blood plasma.
Synonym(s): hyperlipidaemia.
References in periodicals archive ?
001) higher in primary combined hyperlipidaemic individuals than in controls.
The serum lipid levels and CETP activity in normolipidaemic and hyperlipidaemic subjects according to CETP/Taq 1b genotype are shown in Tables III and IV respectively.
2] genotype frequency in our hyperlipidaemic patients, so that the difference with the control group showed a statistically significant difference.
1] allele frequency was significantly higher in hyperlipidaemic group than in control subjects.
It has been documented that genetic variation in lipid and lipoprotein concentrations was associated with the CETP genotypes, in both hyperlipidaemic or normolipidaemic individuals (22,23).
DNA polymorphism around the apo AI gene in normal and hyperlipidaemic individuals selected for a twin study.
Continuous administration of polyphenols from aqueous rooibos (Aspalathus linearis) extract ameliorates dietary-induced metabolic disturbances in hyperlipidaemic mice.
A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects.
Protection by scoparone against the alterations of plasma lipoproteins, vascular morphology and vascular reactivity in hyperlipidaemic diabetic rabbit.
Plumbagin, a known isolate from Plumbago species administered to hyperlipidaemic rabbits reduced serum cholesterol (Sharma et al.
Lipid lowering therapy may also be beneficial in this respect by reversing changes in the clotting pathway, fibrinolytic system and in blood platelets from hyperlipidaemic patients (George, 1995).