hyperleptinemia


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hyperleptinemia

(hī″pĕr-lĕp″tĭn-ē′mē-ă) [″ + ″ + ″]
Excess levels of leptin in the blood. Hyperleptinemia increases body fat content and stimulates appetite.
References in periodicals archive ?
According to Shah and Braverman, "Adiposity and hyperleptinemia are more significant than BMI in predicting high risk obesity.
Leptin decreases plasma paraoxonase 1 (PON1) activity and induces oxidative stress: the possible novel mechanism for proatherogenic effect of chronic hyperleptinemia.
Hyperleptinemia rapidly depletes adipocyte fat in lean rats, whereas comparable hyperleptinemia produced by adipocytes in dietinduced obesity does not, implying a leptinergic blockade in adipocytes during over nutrition.
Hyperleptinemia as a risk factor for high blood pressure in the elderly.
Given that levels of the hormone leptin are normally increased during pregnancy, the authors propose that future research should seek to determine whether BPA directly regulates leptin release from fatty tissue or whether the observed hyperleptinemia is a consequence of the altered metabolic state of these animals.
This metabolic- and inflammatory-mediated injury may result from either resistance to leptin's action in selective tissues, or excess leptin action from adiposity-associated hyperleptinemia.
Gender difference in the relationships among hyperleptinemia, hyperinsulinemia, and hypertension.
2008), or whether the observed hyperleptinemia is a consequence of the altered metabolic state of these animals.
Hyperleptinemia rapidly depletes adipocyte fat in lean rats, whereas comparable hyperleptinemia produced by adipocytes in diet-induced obesity does not, implying a leptinergic blockade in adipocytes during overnutrition.