hyperkeratosis


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hyperkeratosis

 [hi″per-ker″ah-to´sis]
1. hypertrophy of the horny layer of the skin, or any disease characterized by it.
2. hypertrophy of the cornea. adj., adj hyperkeratot´ic.
epidermolytic hyperkeratosis a hereditary autosomal dominant form of ichthyosis, present at birth. Characteristics include generalized redness of the skin and severe hyperkeratosis with small, hard wartlike scales over the entire body, accentuated in areas that flex or bend and sometimes involving the palms and soles. In infancy and childhood, there are recurrent bullae, most often on the lower limbs.
follicular hyperkeratosis a skin condition characterized by excessive development of keratin in hair follicles, resulting in rough, cone-shaped, elevated papules, the openings of which are often closed with a white plug of encrusted sebum. Deficiencies of vitamins A and E, B complex vitamins, and essential fatty acids have all been implicated in the etiology. Called also phrynoderma.
hyperkeratosis lenticula´ris per´stans an autosomal dominant skin disorder, usually occurring in the third or fourth decade of life, characterized by pink, red, or yellow to brown scaly papules on the lower leg and back of the foot, and sometimes on the trunk, thigh, arm, back and palm of the hand, or sole of the foot.

hy·per·ker·a·to·sis

(hī'pĕr-ker'ă-tō'sis),
Thickening of the horny layer of the epidermis or mucous membrane.
See also: keratoderma, keratosis.
Synonym(s): hyperkeratinization

hyperkeratosis

(hī′pər-kĕr′ə-tō′sĭs)
n. pl. hyperkerato·ses (-sēz)
Hypertrophy of the cornea or the horny layer of the skin.

hy′per·ker′a·tot′ic (-tŏt′ĭk) adj.

hyperkeratosis

Dermatology An ↑ in superficial keratinized layers of certain epithelia, skin, and uterine cervix; hyperkeratosis usually represents a reaction to irritation, and generally overlies benign epithelium

hy·per·ker·a·to·sis

(hī'pĕr-ker'ă-tō'sis)
Thickening of the horny layer of the epidermis or mucous membrane.
See also: keratoderma, keratosis
Synonym(s): hyperkeratinization.

hyperkeratosis

Undue thickening of the outer layer of the skin so that a dense horny layer, such as a corn or callosity, results. This is a normal and essentially protective response to local pressure. Hyperkeratosis may also occur as an inherited disorder of the palms and the soles, or as ICHTHYOSIS.

hy·per·ker·a·to·sis

(hī'pĕr-ker'ă-tō'sis)
Thickening of the horny layer of the epidermis or mucous membrane.
References in periodicals archive ?
Histopathologically, VV is characterized by marked verruciform acanthosis and hyperkeratosis. The elongated rete ridges tend to converge toward the center of the lesion ("in-toeing") (Figure 7, A).
So, from this study we have found that squamous metaplasia, hyperkeratosis, and parakeratosis were statistically significant findings in patients with uterine prolapse when compared with patients without prolapse.
Direct microlaryngoscopy and biopsies performed over the ensuing 3 years revealed persistent hyperkeratosis and mild to moderate dysplasia.
Footpad erosion and ulceration have been reported to occur in canine protothecosis [22], but not hyperkeratosis and depigmentation, although footpad biopsies should have been obtained in this case to confirm the presence of Prototheca organisms in those lesions.
[Involment of mucosa in general hyperkeratosis of skin].
A second skin biopsy from the trunk showed focal hyperkeratosis, parakeratosis, erythrocyte extravasation, basal vacuolar degeneration, and perivascular lymphocytic infiltration in the upper dermis (Figure-2b).
In advanced lymphedema, there may be the presence of skin changes such as discoloration, verrucous (wart-like) hyperplasia, hyperkeratosis, and papillomatosis; and eventually deformity (elephantiasis).
The hallmark of TCDD toxicity in humans is chloracne (Panteleyev and Bickers 2006), characterized by epidermal acanthosis and hyperkeratosis, and hyperkeratinization and metaplasia of the sebaceous glands, with comedone formation.
On histological examination of the biopsy obtained, hyperkeratosis in the epidermis, mild erasing in the rete, vacuolar disruption in the basal layer, extensive homogenization in the papillary dermis and chronic inflammation in the reticular dermis was observed and the diagnosis of LS was supported (Figure 2).
A completely clear nail and mycologic cure (the primary endpoint) was defined as no clinical evidence of onychomycosis, as evidenced by a normal toenail plate, no onycholysis, and no subungual hyperkeratosis," to Dr.
By this way, it is possible to assess the density of hair follicles per surface area and to observe the presence of follicular hyperkeratosis (kerosis), as well as comedones, trichostasis spinulosa, intrafollicular bacteria, and mites [7-11].