hyperinsulinism


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Related to hyperinsulinism: Hyperinsulinemia

hyperinsulinism

 [hi″per-in´su-lin-izm″]
1. excessive secretion of insulin by the pancreas, resulting in hypoglycemia.
2. insulin shock from overdosage of insulin.

hy·per·in·su·lin·ism

, hyperinsulinemia (hī'pĕr-in'sū-lin-izm, hī'per-in'syū-lin-ē'mē-ă),
Increased levels of insulin in the plasma due to increased secretion of insulin by the beta cells of the pancreatic islets; decreased hepatic removal of insulin is a cause in some patients, although hyperinsulinism usually is associated with insulin resistance and is commonly found in obesity in association with varying degrees of hyperglycemia.

hyperinsulinism

(hī′pər-ĭn′sə-lə-nĭz′əm)
n.
A condition marked by excessive secretion of insulin by the islets of Langerhans, resulting in hypoglycemia; the symptoms are similar to those of insulin shock, though more chronic in character.

hyperinsulinism

(hī′pər-ĭn′sə-lə-nĭz′əm)

hy·per·in·su·li·ne·mi·a

(hī'pĕr-in'sŭ-lin-ē'mē-ă)
Increased levels of insulin in the plasma due to increased secretion of insulin by the beta cells of the pancreatic islets.
Synonym(s): hyperinsulinism, hyperinsulinaemia.

hy·per·in·su·li·ne·mi·a

(hī'pĕr-in'sŭ-lin-ē'mē-ă)
Increased levels of insulin in the plasma due to increased secretion of insulin by the beta cells of the islets of Langerhans.
Synonym(s): hyperinsulinism, hyperinsulinaemia.

Patient discussion about hyperinsulinism

Q. My husband is diabetic and is living with insulin. He is again having nausea, heartburn, high bloating.. My husband is diabetic and is living with insulin injection. I am paralyzed in one leg and I am home bound. He is the sole earning person in our family to meet our financial needs. He has developed a high stress and depression due to his work which makes him to travel very frequently. He is holding a position in Sales Department. He was given antidepressants. They had helped him to reduce on his stress. But his stomach problems have increased after taking antidepressants. He is again having nausea, heartburn, high bloating and he even eats less as he feels himself full. This is giving stress to him and his depression is increasing again. What do we do? He is living a terrible life.

A. Stomach problem like Gastroparesis is associated with type 1 diabetes. His diabetes with high work related stress has increased his depression problem as well. Persons having antidepressants can have these symptoms of gastro paresis which gets doubled with diabetes. You must meet your doctor and proceed with the treatment. This can also happen due to poor sugar control. He can eat 6-7 meals per day instead of regular three meals this will be of good help.
http://www.youtube.com/watch?v=-5jcOo25ms0&eurl=http://www.imedix.com/health_community/v-5jcOo25ms0_tcoyd_diabetes_gastrointestinal_tract?q=gastro%20paresis%20with%&feature=player_embedded

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References in periodicals archive ?
(9,45) Predominance of the former results in neural sympathetic activity plus hyperinsulinism and hypoglycemia.
It has always been difficult to distinguish between diffuse and focal forms of congenital hyperinsulinism preoperatively, yet the treatment implications are great: focal lesions are curable.
In my earlier publications on diabetogenic hyperinsulinism, I pointed out that this is probably the same disorder seen in different age groups.
To continue with ADHD, the following physical illnesses or mental conditions can reproduce some of the so-called symptoms of that disorder: sleep apnea, lead poisoning, pinworms, caffeinism, hyperthyroidism, learning disorders of various kinds, diets heavy in glucose and other sugars, and hyperinsulinism. And as Kovel (1981) pointed out, the label hyperactivity may be an indicator that a school classroom has little tolerance for normal fidgetiness and the activity levels of well, and appropriately energetic eight- and nine-year-olds.
Construction of a YAC contig encompassing the Usher syndrome type IC and familial hyperinsulinism loci on chromosome 11p14-p15.1.
Metformin; biguanide; diabetes mellitus, non-insulin-dependent; acidosis, lactic; hyperinsulinism. (J Fam Pract 1996; 42:612-618)
As a result, AJ also has apnea (periodic pauses in breathing), bradycardia (slow heartbeat), aspiration (difficulty swallowing correctly), paralyzed vocal cords and hyperinsulinism production of excessive insulin, the hormone that regulates blood sugar levels).
Other similarities to diabetes in Native Americans were suggested, including the influence of obesity, particularly upper-body obesity, a westernized lifestyle, and the presence of hyperinsulinism.
Dysfunction of the [K.sub.ATP] channel can cause either congenital hyperinsulinism (CHI) or diabetes (neonatal or adult onset) (1,4,5,6,7,8,9).
Biotechnology company Zealand Pharma A/S (CPH:ZEAL) (NYSE:ZEAL) announced on Friday the receipt of approval from the US Food and Drug Administration (FDA) for the company's Investigational New Drug (IND) application for initiation of two phase 3 clinical trials of dasiglucagon in CHI (congenital hyperinsulinism).
Because of the inhibitory effect of both insulin and insulin-like growth factor-1 on SHBG secretion by Hep G2 cells in vitro, it has been proposed that SHBG levels could be a marker of insulin resistance and/or hyperinsulinism in humans.
In my patients with cancer, I find some degree of hyperinsulinism in nearly all patients, usually beginning within months of the onslaught of fears and doubts, real or imagined, concerning cancer diagnosis as well as the toxicity and efficacy of treatment options.