Strongyloides stercoralis
hyperinfection could mimic accelerated idiopathic pulmonary fibrosis.
3]
Hyperinfection denotes autoinfection with accelerated gastrointestinal and pulmonary symptoms.
3) It can cause autoinfection, chronic persistent infection,
hyperinfection (with involvement of the lung and the gastrointestinal system), and disseminated infection involving other organs.
5) Literature describes SS infection as chronic and asymptomatic, but a change in immune status can lead to an increase in parasite load,
hyperinfection syndrome, dissemination, and death.
It has the ability to autoinfect the host and can cause
hyperinfection in those who are immunocompromised.
Immunosuppressed persons can develop strongyloides
hyperinfection syndrome, which can be fatal (1).
Hyperinfection syndrome develops when immunosuppression reduces the immune surveillance and results in augmentation of the normal life cycle of the parasite leading to a dramatic increase in the density of the larvae.
Administration of corticosteroids to a patient who harbors chronic Strongyloides infection can precipitate
hyperinfection and dissemination of the parasite, yielding a 50-80 percent mortality rate, depending on other host conditions.
haematobium 118 7 66 Filaria Strongyloides 195 34 78 Simple intestinal 191 34 78
Hyperinfection 4 0 0 Non-Strongyloides 140 102 6 Loa loa 86 82 1 Onchocerca volvulus 21 12 0 Other 31 9 4 Wucheria bancrofti 4 1 1 Vaccine-preventable disease 146 9 47 Hepatitis A 59 3 14 Influenza 24 0 11 Measles 5 0 0 Typhoid fever ([dagger]) 58 6 22 Bite wounds ([double dagger]) 193 5 47 Bite wounds necessitating rabies 184 4 38 prophylaxis Source of bite Dog 91 4 17 Cat 46 0 8 Other ([paragraph]) 56 1 22 Dengue (uncomplicated) 113 6 46 Tuberculosis 86 2 33 Pulmonary 43 2 14 Extrapulmonary 24 0 13 Miliary, disseminated 13 0 4 Meningitis 5 0 2 Multidrug resistant# 1 0 0 Acute HIV infection 44 4 21 Illness/incident Total No.
Disseminated Strongyloides stercoralis:
hyperinfection during medical immunosuppression.
Subcutaneous ivermectin as a safe salvage therapy in Strongyloides stercoralis
hyperinfection syndrome.
89) In southern Africa, a recent article reported this parasite in the HIV setting with
hyperinfection leading to mesenteric lymphadenopathy and intestinal pseudo-obstruction.
