The second familial syndrome,
hyperimmunoglobulinemia D with periodic fever syndrome, or hyper IgD (HIDS), has an early age of onset, typically before 12 months and with more than half before 6 months.
Hyper-immunoglobulin A in the hyperimmunoglobulinemia D syndrome.
Simvastatin treatment for inflammatory attacks of the hyperimmunoglobulinemia D and periodic fever syndrome.
Delayed eruption of permanent teeth in hyperimmunoglobulinemia E recurrent infection syndrome.
High-dose intravenous gamma-globulin treatment for hyperimmunoglobulinemia E syndrome.
Hyperimmunoglobulinemia D with###Mevalonate kinase###Fever associated with###IL-1 and TNF
A founder effect in the
hyperimmunoglobulinemia D and periodic fever sydrome.
AA amyloidosis also complicates 4 hereditary diseases with varying frequencies: FMF, the tumor necrosis factor receptor-associated periodic syndrome, Muckle-Wells syndrome, and
hyperimmunoglobulinemia IgD with periodic fever.
The international hyper-IgD study group:
hyperimmunoglobulinemia D and periodic fever syndrome.
1] Not only does CRMO have similarities to familial Mediterranean fever (FMF), but it also presents with other periodic fever syndromes, such as tumor necrosis factor receptor-associated periodic syndrome (TRAPS), and
hyperimmunoglobulinemia D with periodic fever syndrome (HIDS)(2) since all these are considered to be autoinflammatory diseases.
Atopic dermatitis impostors can include contact dermatitis, scabies, Wiskott-Aldrich syndrome,
hyperimmunoglobulinemia E, and Netherton's syndrome.
The
hyperimmunoglobulinemia D and periodic fever syndrome is proposed to be caused by a defect in the activity of mevalonate kinase enzyme which is involved in cholesterol and non-sterol isoprenoid biosynthesis.
