A novel treatment candidate, SGX301, which uses synthetic
hypericin as its active ingredient, is a photodynamic therapy that is activated by safe, visible light.
Hypericin and its companion pseudohypericin have proven anti-viral activities.
* Anthraquinone (naphthodianhrones) derivatives:
hypericin, pseudohypericin, protopseudohypericin, protopseudoacetic acid, isohypericin, and cyclopseudohypericin,
(14) concluded that giving the active component,
hypericin (14.2 and 142.0 ng/mL), to embryo cultures was teratogenic on rat embryos.
Chemical constituents: Volatile oil,
hypericin, and pseudohypericin, flavonoids (Khare, 2007; Prajapati et al., 2003; Baquar, 1989).
In recent years, our group has identified sonosensitizers derived from extracts of Chinese herbs, including
hypericin, curcumin, and hydroxyl acetylated curcumin [2, 20, 21].
The most important secondary metabolites present in the drug are phloroglucinols (hyperforin, adhyperforin), naphtodianthrones (
hypericin, pseudohypericin), flavonoids (rutin, quercetin, quercitrin, isoquercitrin, hyperoside, and amentoflavone), phenolic acids, and small amounts of essential oil.
The oil will eventually take on the ruby-red color of its active constituent,
hypericin. After 2 weeks, squeeze the contents through 4 layers of cheesecloth into a clean bowl, pour the oil into a clean gallon jar, and allow it to settle overnight.
For food flavorings, the only class of compounds with usage restrictions by regulatory bodies to some of its constituents is the extraction solvent class, where the agaric acid, aloin, beta-azarone, berberine, coumarin, hydrocyanic acid,
hypericin, pulegone, quassine, safrole and isosafrole, santonin and tuyona alpha and beta have maximum tolerable limits discriminated in documents (Brasil, 1999; Brasil, 2007).
Hypericin, hyperforin, and adhyperforin contained in St.
The most important active ingredients of hypericum are
hypericin and pseudohypericin.
Hypericin for visualization of high grade gliomas: first clinical experience.
