neuronal hyperplasia

(redirected from hyperganglionosis)

neu·ro·nal hy·per·pla·si·a

increased numbers of ganglion cells with myenteric plexus hyperplasia and increased acetylcholinesterase activity in nerves of the mucosa and submucosa. Clinically, neuronal hyperplasia mimics Hirschsprung disease. Similar findings are seen in patients with multiple endocrine neoplasia syndrome, type IIB, and in neurofibromatosis.
References in periodicals archive ?
There was no problem/ controversy regarding diagnosis of aganglionosis but when we talk of ganglionic segments actually it may include the normal number of ganglion cells and allied HDs, which are hypoganglionosis, hyperganglionosis and immature ganglion cells.
Key words: Hirschsprung's disease (HD), hypoganglionosis, hyperganglionosis (IND type B) and immaturity of ganglion cells (IGC).
Congenital intestinal neuronal disturbances have been classified as aganglionosis (Hirschsprung's di sease), hyperganglionosis (Intestinal Neuronal Dys plasia), hypoganglionosis, ganglion cell immaturity, combined forms and certain unclassifiable forms.