hypergammaglobulinemia


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hypergammaglobulinemia

 [hi″per-gam″ah-glob″u-lin-e´me-ah]
increased gamma globulins in the blood. adj., adj hypergammaglobuline´mic.
monoclonal h's an excess of homogeneous immunoglobulin molecules of a single specificity in the blood following proliferation of a clone of immunoglobulin-producing cells.

hy·per·gam·ma·glob·u·lin·e·mi·a

(hī'pĕr-gam'ă-glob'yū-lin-ē'mē-ă),
An increased amount of the γ-globulins in the plasma, such as that frequently observed in chronic infectious diseases.

hypergammaglobulinemia

/hy·per·gam·ma·glob·u·lin·emia/ (-gam″ah-glob″u-lĭ-ne´me-ah) increased gamma globulins in the blood.hypergammaglobuline´mic
monoclonal hypergammaglobulinemias  plasma cell dyscrasias.

hypergammaglobulinemia

(hī′pər-găm′ə-glŏb′yə-lə-nē′mē-ə)
n.
An increased concentration of gamma globulins in plasma, as in chronic infectious diseases.

hy·per·gam·ma·glob·u·lin·e·mi·a

(hī'pĕr-gam'ă-glob'yū-lin-ē'mē-ă)
An increased concentration of gammaglobulins in the plasma.
Synonym(s): hypergammaglobulinaemia.

hy·per·gam·ma·glob·u·lin·e·mi·a

(hī'pĕr-gam'ă-glob'yū-lin-ē'mē-ă)
Increased γ-globulins in plasma, as in chronic infectious diseases.
Synonym(s): hypergammaglobulinaemia.

hypergammaglobulinemia

increased gamma globulins in the blood.

mink hypergammaglobulinemia
monoclonal hypergammaglobulinemia
an increased level of homogeneous immunoglobulin molecules of a single specificity in the blood following proliferation of a clone of immunoglobulin-producing B lymphocytes. See also gammopathy.
References in periodicals archive ?
The liver, spleen, and bone marrow are affected, and the disease is characterized by fever, weight loss, hepatosplenomegaly, pancytopenia, and hypergammaglobulinemia (2).
Conclusion: Hypergammaglobulinemia is a marker of extraintestinal manifestations in pediatric inflammatory bowel disease and may assist in distinguishing arthritis from arthralgia.
Autoimmune pancreatitis is a chronic inflammatory disorder of unknown etiology associated with hypergammaglobulinemia that leads to fibrosis and organ dysfunction.
Clinical symptoms, leukocytosis, eosinophilia, and hypergammaglobulinemia should all be evaluated before further testing.
Laboratory findings include hypergammaglobulinemia, ANA antibodies [greater than or equal to] 1:320, serum anti-Ro (SS-A) and anti-La (SS-B) antibodies and a positive rheumatoid factor [5].
Clinical characteristics often include a painless cervicallymphadenopathy, fever, leukocytosis, an elevated erythrocyte sedimentation rate, and polyclonal hypergammaglobulinemia.
Hypergammaglobulinemia in Leishmania donovani infected hamsters: possible association with a polyclonal activator of B cells and with suppression of T cell function.
In patients with polyclonal hypergammaglobulinemia (as determined by serum protein electrophoresis and immunofixation electrophoresis), nonspecific increases in FLCs occurred in a fashion similar to the nonspecific increases in CRP seen with inflammation.
14) In Woulters et al's study, all JIA patients had hypergammaglobulinemia consistent with B cell hyperactivity.
Laboratory test results show marked eosinophilia, anemia, hypergammaglobulinemia, and increased titers to A and B blood group antigens.
Gaucher disease can be associated with hyperactivity of the immune system, which manifests with polyclonal hypergammaglobulinemia or mono-clonal gammopathies (11).