The acute, hyperemetic phase is characterized by severe nausea, frequent vomiting, abdominal pain, and compulsive bathing for temporary symptom relief.
The pathogenesis of paradoxical hyperemetic symptoms of CHS remain unclear, but several mechanisms have been proposed.
Treatment of acute hyperemetic episodes in CHS primarily is supportive; address dehydration with IV fluids and electrolyte replenishment as needed.
Acute, hyperemetic episodes are ideal teachable moments because of the acuity of symptoms and clear association with Cannabis use.
CHS patients often present during acute hyperemetic episodes, occuring every four to eight weeks, with symptom-free periods