To attenuate hyperdynamic
response during ECT, many pharmacological agents such as beta blockers, alpha-2 agonists, vasodilators and local anaesthetics were tried.
Moreover, coming off cardiopulmonary bypass, she was hypovolemic, which led to a hyperdynamic
Subsequent studies reported positive effects of thoracic epidural anaesthesia on pulmonary endothelial capillary integrity in septic rats in the hyperdynamic
phase, modulating the production of nitric oxide (effects not found in rats with sepsis in the hypodynamic phase) (26).
Furthermore, in addition to hypoxia/ischemia, they also noticed the possible serious effect of sudden fluctuations in cerebral blood flow and arterial blood pressure (hyperdynamic
circulation) on the intracranial hemorrhage.
LVP in patients with cirrhosis and RA further enhances the preexisting hyperdynamic
circulation, via a counter-regulatory overactivation of vasoconstrictor systems.
There were also regional wall motion abnormalities which included hypokinetic to akinetic basal myocardial segments, akinetic apex, and hyperdynamic
midventricular segments which can be visualized in Figures 2-4.
Whilst the severity of hypoxia at presentation was probably exacerbated by acute pulmonary oedema, the ongoing hypoxia (despite successful diuresis), and consistently hyperdynamic
circulation suggested the underlying pathology might be more complicated.
The patient was ill-appearing, with mild dry mouth, hyperdynamic
heart beats without murmurs, and tenderness in the right-sided costovertebral angle.
Researchers also found that iPSC-CMs feature more active genes and a higher number of genes poised to be either activated or repressed (known as "epigenetically hyperdynamic
"), a trait more commonly found in potent cells.
Histological examination during the autopsy of children with AM showed pulmonary artery pathology, including muscular hypertrophy of large- and medium-sized pulmonary arterial branches, severe stenosis of the distal pulmonary arterioles, microthrombotic occlusion of small arteries, and necrotizing arteritis.[sup], These putative mechanisms can result from several factors, including circulating vasoactive mediators, blood volume overload, and hyperdynamic
Dr Alhimairi added: "People who do not consume enough water may face dehydration, hypotension, fast heart rate due to hyperdynamic
circulation, angina due to workload on the heart, and worsened heart failure status as they may need admissions to hospital for stabilisation.
Development of hyperdynamic
circulation and response to beta blockers in compensated cirrhosis with portal hypertension.