In contrast, phytosterols (i.e., sitosterol and stigmasterol) are reduced in hyperthyroidism owing to gastrointestinal effects of thyroid hormones, which promote gut motility resulting in hyperdefecation
. Conversely, impaired bowel transit occurs in hypothyroidism (3).
All oral and some IM/IV antibiotics which are enterohepatically re-circulated into the GI tract after infection can commonly cause conditions ranging from early-onset hyperdefecation
to diarrhea within 1-7 days after the start of oral or IV therapy.
Over the preceding 2 months, the patient had experienced a 4.5-kg weight loss despite increased appetite, mild heat intolerance, palpitations, an increase in her long-standing hand tremor, intermittent anxiety, hyperdefecation
, and light menstrual flow.