hyperchromatism


Also found in: Dictionary, Encyclopedia, Wikipedia.

hyperchromatism

 [hi″per-kro´mah-tizm]
1. excessive pigmentation.
2. degeneration of cell nuclei, which become filled with particles of pigment, or chromatin.
3. increased staining capacity. adj., adj hyperchromat´ic.

hy·per·chro·ma·tism

(hī'pĕr-krō'mă-tizm),
1. Excessive pigmentation.
2. Increased staining capacity, especially of cell nuclei for hematoxylin.
3. An increase in chromatin in cell nuclei.
[hyper- + G. chrōma, color]

hyperchromatism

/hy·per·chro·ma·tism/ (-kro´mah-tizm)
1. excessive pigmentation.
2. degeneration of cell nuclei, which become filled with particles of pigment (chromatin).
3. increased staining capacity.hyperchromat´ic

hyperchromatism

(hī′pər-krō′mə-tĭz′əm) or

hyperchromia

(-mē-ə)
n.
Excessive formation of skin pigment.

hy′per·chro·mat′ic (-krə-măt′ĭk) adj.

hy·per·chro·ma·tism

(hī'pĕr-krō'mă-tizm)
1. Excessive pigmentation.
2. Increased staining capacity, especially of cell nuclei for hematoxylin.
3. An increase in chromatin in cell nuclei.
Synonym(s): hyperchromasia, hyperchromia.
[hyper- + G. chrōma, color]

hyperchromatism

1. excessive pigmentation.
2. degeneration of cell nuclei, which become filled with particles of pigment, or chromatin.
3. increased staining capacity.
References in periodicals archive ?
1) Hyperchromatism of the basal cell nuclei of the epithelium lining the cystic cavity.
Nuclear hyperchromatism and an irregular chromatin distribution are seen, and there is an increase in the size and number of irregularly shaped nuclei.
Nuclear hyperchromatism and crowding are features of all adenomas.
Although the tumor cells showed an infiltrative growth pattern like malignant tumor, the majority of the tumor cells showed little nuclear and cytoplasmic pleomorphism, nuclear hyperchromatism, mitotic activity or extensive necrosis of the tumor nests, and the positivity for Ki-67 was weak.
The degree of nuclear pleomorphism, hyperchromatism, and number of mitoses in CCOC are quite variable.
B, Nuclear pseudostratification, crowding, and hyperchromatism with brisk mitotic activity in apical location and numerous apoptotic bodies are seen (hematoxylin-eosin, original magnifications X100 [A] and X200 [B]).
It showed cystic lining with columnar basal cells, nucleus palisading with polarization and hyperchromatism, cytoplasmic vacuolization with intercellular spacing.
Depending on the type and grade of a particular tumor, the cells may exhibit pleomorphism, a high nucleus-to-cytoplasm ratio, hyperchromatism, and abnormal mitoses.
The author also noted many atypical epithelial cells with enlarged nuclei and hyperchromatism might have originated from the proliferating ductal epithelium.
A few cells showed features of dysplasia such as cellular and nuclear pleomorphism with nuclear hyperchromatism (Figure 5).
8) Random cytologic atypia with individual nuclei displaying enlargement and hyperchromatism is present in a number of cases, particularly in younger individuals.
nuclear mitotic activity, hyperchromatism, and cellular pleomorphism.