hypercholesterolaemia


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Related to hypercholesterolaemia: hyperlipidaemia, Familial hypercholesterolaemia

hy·per·cho·les·ter·ol·e·mi·a

(hī'pĕr-kŏ-les'tĕr-ol-ē'mē-ă)
The presence of an abnormally large amount of cholesterol in the blood.
Synonym(s): hypercholesteremia, hypercholesterolaemia

hypercholesterolaemia

Abnormally high levels of CHOLESTEROL in the blood. This may be dietary or may, rarely, be due to an inherited defect. See also HYPERLIPIDAEMIA.

hypercholesterolaemia

abnormally high levels of plasma cholesterol (>5.2 mmol/L); hypercholesterolaemia (especially raised low-density lipoprotein [LDL] cholesterol fraction in plasma) correlates with increased incidence and risk of atherosclerosis (see high-density lipoprotein cholesterol; low-density lipoprotein)

hy·per·cho·les·ter·ol·e·mi·a

(hī'pĕr-kŏ-les'tĕr-ol-ē'mē-ă)
The presence of an abnormally large amount of cholesterol in the blood.
Synonym(s): hypercholesteremia, hypercholesterolaemia.
References in periodicals archive ?
The Phase III, active-controlled study was conducted for 12 weeks to compare the safety and efficacy of pitavastatin (1 mg, 2 mg and 4 mg) and pravastatin (10 mg, 20 mg and 40 mg) in patients aged greater than or equal to 65 years with primary hypercholesterolaemia or combined dyslipidaemia.
Estimation of the prevalence of familial hypercholesterolaemia in a rural Afrikaner community by direct screening for three Afrikaner founder low density lipoprotein receptor gene mutations.
Amgen is working with the National Institute for Health and Care Excellence (NICE) in its review of the use of evolocumab for the treatment of primary hypercholesterolaemia and mixed dyslipidaemia.
Occasionally, severe dyslipidaemia may be precipitated by glucocorticoid treatment, and in this setting special treatment with statins will be required for LDL hypercholesterolaemia, or fibrates for severe hypertriglyceridaemia.
There is a higher risk of atherosclerosis and patients are prone to have hypertension, glucose intolerance and hypercholesterolaemia.
Pseudohyponatraemia, hypercholesterolaemia, and primary biliary cirrhosis.
Familial hypercholesterolaemia is a genetic disorder that can affect up to one in 500 people and leads to high cholesterol, even in children.
In this issue Chou and colleagues (7) report on a Taiwanese referral-based study demonstrating that unlike the apnoea hypopnoea index; the oxygen desaturation index defined as the frequency of 4 per cent oxygen desaturation episodes per hour of sleep was significantly associated with hypercholesterolaemia (>200 mg/dl) and hypertriglyceridaemia (>150 mg/dl) even after taking into account confounding factors such as obesity as defined by body mass index.
The pioneering drop-in centre will provide advice and support to everyone who is concerned about cholesterol and inherited high cholesterol conditions such as familial hypercholesterolaemia.