hypercapnic ventilatory response

hypercapnic ventilatory response

The ratio of the change in minute volume to deltaP(aCO2).
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This test could be useful to predict weaning failure if the combined hypercapnic respiratory drive and hypercapnic ventilatory response values were below the threshold values.
Only when the hypercapnic respiratory drive and hypercapnic ventilatory response were below the threshold values was this test found to be useful to predict weaning failure.
In our study, the mean values of hypercapnic response, compared with other studies with non-intubated healthy subjects (19,20), is clearly lower, especially for the hypercapnic ventilatory response value.
However, this could explain the low hypercapnic ventilatory response but not the low hypercapnic drive response (19).
Our study has several limitations: first, the limited number of patients studied; second, the wide normal ranges described for hypercapnic stimulation indices (19,20), the large day-to-day intra-individual variation in breathing pattern parameters (36), the within-day variability of hypercapnic ventilatory response and the coefficient of variation that ranges from 8.
E] to hypercapnia (Figure 1) and lower hypercapnic respiratory drive response and hypercapnic ventilatory response value than successfully weaned COPD patients (Table 2).
3%) with hypercapnic respiratory drive response and hypercapnic ventilatory response lower than the threshold value failed the weaning process, whereas 18 of 29 patients (62.
2] is higher during sleep than wakefulness, and the hypercapnic ventilatory response curve is shifted to the right throughout all stages of sleep as compared with wakefulness.
We have shown abnormalities in both awake hypoxic and hypercapnic ventilatory responses in the methadone patients that would lead to this instability," Dr.