CO2 response test

(redirected from hypercapnic response test)

CO2 response test

A clinical test which measures the hypercapnic drive response—the ratio of the change in airway-occlusion pressure 0.1 second after the start of inspiratory flow [deltaP(0.1)] to the change in P(aCO2) [deltaP(aCO2)]—and the hypercapnic ventilatory response—the ratio of the change in minute volume to deltaP(aCO2). A reduced CO2 response, as measured by hypercapnic drive response and hypercapnic ventilatory response, are associated with prolonged weaning from mechanical ventilation.
References in periodicals archive ?
The simple measure of basal [P.sub.a]C[O.sub.2] showed better or similar accuracy to the hypercapnic response test. Only when the hypercapnic respiratory drive and hypercapnic ventilatory response were below the threshold values was this test found to be useful to predict weaning failure.