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In males younger than 10 years, the only manifestation of the disease may be asymptomatic LMW proteinuria and/or hypercalciuria.
9 Medullary nephrocalcinosis along with persistent hypercalciuria, sooner or later, will develop in nearly all NBS patients.
Unless one has hypercalciuria type II and hyperoxaluria (primary and enteric), there is no reason to avoid healthful foods that contain natural oxalates found in plants.
We excluded patients (1) with primary hyperparathyroidism (HPT); (2) without pre- and post-VDCS metabolic stone workup; (3) with hypercalciuria (urinary calcium excretion >300 mg/d for men, >275 mg/d for women) prior to VDCS; (4) on thiazide diuretic prior to VDCS; and (5) pregnant women (Fig.
Frequencies and percentages were calculated for categorical variables such as gender and presence of hypercalciuria, hyperoxaluria, hyperuricosuria and hypocitraturia.
Effects of low-calcium diet on urine calcium excretion, parathyroid function and serum 1, 25 (OH)2D3 levels in patients with idiopathic hypercalciuria and in normal subjects.
In the past, several phenotypic variants of Dent's disease were independently described and named as separate disorders, including X-linked recessive nephrolithiasis with renal failure, X-linked recessive hypophosphatemic rickets and familiar idiopathic LMW proteinuria with hypercalciuria in Japanese patients [2].
Hypercalciuria (Ca>300 mg/day in men and >250 mg/day in women) was not reported in participant with less than 2.
Reference values for urinary calcium excretion and screening for hypercalciuria in children and adolescents.
Hypercalcaemia is observed in up to 11% of patients; however, hypercalciuria is more frequent (40% of patients) and renal calculi are not uncommon (10%).
Hypercalciuria and a higher calcium/creatinine ratio are found mainly in osteoporotic groups, but bone mineral density (BMD) and osteoporosis percentages in the postmenopausal period are similar between hypertensive and normotensive women.
Hypercalcemia occurred in 9% of patients and hypercalciuria developed in 33%.