Miyahira et al., "Remodeling of hepatic metabolism and hyperaminoacidemia
in mice deficient in proglucagon-derived peptides," Diabetes, vol.
Wolfe, "The response of muscle protein anabolism to combined hyperaminoacidemia
and glucose-induced hyperinsulinemia is impaired in the elderly," Journal of Clinical Endocrinology and Metabolism, vol.
Casein, in contrast, is a 'slow' protein, inducing a prolonged plateau of moderate hyperaminoacidemia
. When casein reaches acid in the stomach, the pH level drops and causes the ingested protein bolus to clot, slowing the rate at which the protein is absorbed into the body.
The response of muscle protein anabolism to combined hyperaminoacidemia
and glucoseinduced hyperinsulinemia is impaired in the elderly.
In the presence of hyperaminoacidemia
, insulin appears to promote protein synthesis by aiding the amino acids' entry into cells and through tangential signaling resulting from the PI3K pathway.
effects on intestinal transport of related amino acids.
Euglycemic Hyperinsulinemia Augments Amino Acid Uptake by Human Leg Tissues during Hyperaminoacidemia
(15.) It can lead to hyperammonemia and hyperaminoacidemia
with nausea, diarrhoea and even death (Cordain et al 2002a:46).
(2006) Hyperinsulinaemia, hyperaminoacidemia
and post-exercise muscle anabolism: The search for the optimal recovery drink.