hygiene hypothesis


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The theory that the clean modern lifestyle and lack of early childhood exposure to dirt, bacteria and other pathogens weaken the immune system, and increase susceptibility to allergies and asthma

hygiene hypothesis

Allergy medicine The theory that a clean modern lifestyle alters the immune system, ↑ susceptibility to allergies. See Leipzig disparity.

hy·giene hy·poth·e·sis

(hī'jēn hī-poth'ĕ-sis)
The tenet that improved cleanliness and modern medical care may be lowering the ability of people to deal with otherwise nonlethal pathogens and disease.

hygiene hypothesis,

n the theory that excessive prevention of early childhood exposure to dirt and pathogens can stunt the development of the immune system.
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While there are still uncertainties regarding the exact cause of allergies, the hygiene hypothesis theory looks at how increased levels of hygiene and the overuse of antibiotics may affect allergies, explained Tipper.
According to a research hypothesis called the hygiene hypothesis, the newborn baby's immune system in this way learns to distinguish between its own harmless molecules and foreign molecules.
According to Mroueh, children nowadays were developing more allergies and he put this down to the controversial hygiene hypothesis, which suggests children are growing more susceptible to allergies due to lack of exposure to infectious agents.
The findings represent a microbial twist in the hygiene hypothesis, which argues that a less-than-sanitary early life may prime a child's immune system against overreacting to grass, dust mites and other ordinary substances.
The hygiene hypothesis is the reason investigators are heading down this path.
The hygiene hypothesis was introduced in 1989 by Strachan, who noted that a reduction in childhood infections might have led to an increase in adulthood allergies.
Knowing what I know about the hygiene hypothesis, I think twice before I run to a physician for an antibiotic," she says.
This further advances the hygiene hypothesis that early childhood exposure to microorganisms affects the immune system's development and onset of allergies," said Christine Cole Johnson, Ph.
The IFH report, entitled 'The hygiene hypothesis and its implications for home hygiene, lifestyle and public health', reviewed evidence that has come to light over the last 20 years, since the 'hygiene hypothesis' was first proposed.
Alternately, the hygiene hypothesis posits that the modern obsession with cleanliness is as much a problem as house dust mites.
Thirteen contributions from authors directly involved in the original investigations report on such topics as the hygiene hypothesis revisited, loss-of-function mutations within the filaggrin gene, the antimicrobial skin barrier, defective sweating responses, the role of cytokines/chemokines in pathogenesis, biomarkers for itch and disease severity, and practical issues on interpretation of scoring systems, among other topics.
One common theory is the hygiene hypothesis, which posits that excessive hygiene is responsible for the increase of allergies and other immune-mediated diseases.