ODF were prepared by using hydroxypropyl methylcellulose
and polyvinyl alcohol and different superdisintegrants at a specific proportion.
In all cases combination of 1% sodium hyaluronate (Provisc, Alcon) and 2% hydroxypropyl methylcellulose
(Viscot, Alcon) was used as viscoelstics.
Figure 3 shows the Tg versus percent relative humidity profiles for an API manufactured in Eudragit L100 at a 60% API loading compared to the same API manufactured in a hydrophobic grade of hydroxypropyl methylcellulose
acetate succinate (HPMCAS) at the same loading.
For example, drugs with high lattice energy and weak bases that are in their protonated form in the gastric juice, but crystallize at the higher pH of the intestinal environment, are suitable candidates for the formation of supersaturated solutions with hydroxypropyl methylcellulose
(HPMC) as a crystallization inhibitor.
Quality and Safety of Citrus sinensis coated with Hydroxypropyl Methylcellulose
edible coatings containing Moringa oleifera Extract Stored at Ambient Temperature.
and maltodextrin were used as the wall materials.
Then, the extract was formulated into the base of the peel-off mask gel containing variations in concentration of polyvinyl alcohol (7%, 9%, and 10%) and hydroxypropyl methylcellulose
(2% and 2.5%).
The strategy in this case was to combine hydroxypropyl methylcellulose
(HPMC) as the structuring agent of the coating with a beeswax that provided hydrophobicity, thus reducing weight loss and incorporating three different antifungal agents with proven activity.
His usual topical treatment consists of olopatadine twice daily and hydroxypropyl methylcellulose
6 hourly in both eyes.
The highest quantity of model active compound (calcium dobesilate, CD) was released from the hydrogel based on a hydroxypropyl methylcellulose
(HPMC), 82% after 250 min, and similarly in the case of MC and PC-11 the gels released around 81% after 250 min .