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an amino acid produced in the digestion of hydrolytic decomposition of proteins, especially of collagens.
hydroxyproline/hy·droxy·pro·line/ (-pro´lēn) a hydroxylated form of proline, occurring in collagen and other connective tissue proteins.
an amino acid whose level in the urine is elevated in diseases of the bone and certain genetic disorders, such as Marfan's syndrome. Its normal accumulation in urine after a 24-hour collection is 10 to 75 mg.
hydroxyprolineBiochemistry A hydroxylated amino acid which is most concentrated in collagen ↑ in urine Indicates ↑ turnover of bone matrix, often caused by osteoporosis ↓ in Malnutrition, ↑ by acromegaly, acute osteomyelitis, burns, congenital hyperphosphatasia, fibrous dysplasia, healing fractures, hyperparathyroidism, hyperthyroidism, Marfan syndrome, osteomalacia, Paget's disease of bone, parathyroid adenoma, rickets, bone tumors
Hyp; an amino acid derived from proline.