hydroxylation


Also found in: Dictionary, Encyclopedia, Wikipedia.

hy·drox·yl·a·tion

(hī-drok'si-lā'shŭn),
Placing of a hydroxyl group on a compound in a position where one did not exist before.

hydroxylation

addition of −OH groups to a molecule.
References in periodicals archive ?
1980) Studies on the steroid hydroxylation system in adrenal cortex microsomes.
15-17) In addition to facilitating the hydroxylation reactions involved in collagen formation, vitamin C also stimulates collagen synthesis by enhancing collagen gene transcription.
Debrisoquin and S-mephenytoin hydroxylation phenotypes and CYP2D6 genotypes in an Estonian population.
Hydroxylation of praline and lysine residues in collagens and other animal and plant proteins.
CONCLUSIONS: There seem to be three metabolic pathways: cleavage of the diphenyl ether bond, hydroxylation, and debromination/hydroxylation.
Comparison of O-dealkylation of 7EOC and the hydroxylation of benzo([Alpha])pyrene in human placenta: effect of cigarette smoking.
In the environment, it undergoes hydrolysis plus ring and methyl group hydroxylation, and is therefore not persistent.
We now own the IP from the agreement, including the proprietary database of about 500 metabolism measurements used in building our predictions for the hydroxylation reaction caused by a family of enzymes known as Cytochrome P450s, and about 900 compounds used to build our substrate classification (i.
Interestingly, hydroxylation of coumarin markedly affects the anti-biofilm effect (Fig.
The determination of xanthine oxidase inhibitory activity of test samples was measured by the rate of hydroxylation of the substrate (xanthine) and subsequent formation of uric acid, which is a colorless product absorbing at 295 nm [21].