hydrops fetalis


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Related to hydrops fetalis: erythroblastosis fetalis

hydrops

 [hi´drops] (L.)
old term for edema. adj., adj hydrop´ic.
fetal hydrops (hydrops feta´lis) gross edema of the entire body of the newborn infant, in erythroblastosis fetalis.

fe·tal hy·drops

, hydrops fetalis
abnormal accumulation of serous fluid in the fetal tissues, as in erythroblastosis fetalis.

hydrops fetalis

massive edema in the fetus or newborn, usually in association with severe erythroblastosis fetalis. Severe anemia and effusions of the pericardial, pleural, and peritoneal spaces also occur. The condition usually leads to death, even with immediate exchange transfusions after delivery. Also called fetal hydrops.

hydrops fetalis

Kernicterus, Rh incompatibility, Rh-induced hemolytic disease of newborn Obstetrics An accumulation of fluid in neonates, resulting in a 'puffy', plethoric or hydropic appearance that may be due to various etiologies Clinical Ascites, edema, ↓ protein or chronic intrauterine anemia, hepatosplenomegaly, cardiomegaly, extramedullary hematopoiesis, jaundice, pallor COD Heart failure. See Hemolytic disease of the newborn.
Hydrops Fetalis, causes
Immune Mother produces IgG antibodies against infant antigen(s), often an RBC antigen, most commonly, anti-RhD, which then passes into the fetal circulation, causing hemolysis
Non-immune Hydrops may result from various etiologies including
•  Fetal origin, eg congenital heart disease (premature foramen ovale closure, large AV septal defect), hematologic (erythroblastosis fetalis, α-thalassemia due to hemoglobin Barts, chronic fetomaternal or twin-twin transfusion), infection (CMV, herpesvirus, rubella, sepsis, toxoplasma), pulmonary (cystic adenomatoid malformation, diaphragmatic hernia, with pulmonary hypoplasia, lymphangiectasia), renal (vein thrombosis, congenital nephrosis) and teratomas, skeletal malformations (achondroplasia, osteogenesis imperfecta, fetal neuroblastomatosis, storage disease, meconium peritonitis, idiopathic)
•  Placental Chorangioma, umbilical or chorionic vein thrombosis
 Maternal DM, toxemia  

fe·tal hy·drops

, hydrops fetalis (fē'tăl hī'drops, fē-tā'lis)
Abnormal accumulation of serous fluid in the fetal tissues, as in erythroblastosis fetalis.

hydrops fetalis

The most severe form of HAEMOLYTIC DISEASE OF THE NEWBORN. The fetus dies in the womb from the overwhelming toxic effect of the BILIRUBIN released during excessive breakdown of red blood cells. See also RHESUS FACTOR.

Hydrops fetalis

A condition in which a fetus or newborn baby accumulates fluids, causing swollen arms and legs and impaired breathing.
References in periodicals archive ?
A 26-year-old gravida 3, para 1, abortus 2 woman was referred to the hospital at the 20th week of gestation because of hydrops fetalis.
Frequency of parvovirus B19 infection in nonimmune hydrops fetalis and utility of three diagnostic methods.
Successful management of a large fetal mediastinal teratoma complicated by hydrops fetalis.
Detection of [alpha]-thalassemia in [beta]-thalassemia carriers and prevention of Hb Bart's hydrops fetalis through prenatal screening.
In fact, clinical decision-making for pregnancies at risk for Hb Barts hydrops fetalis has been changing in regions with a high prevalence of [alpha]-thalassemia.
Researchers have described fetuses that have undergone a process similar to isoimmunization, which has lead to hydrops fetalis and death (Gillette, 1993).
11] Sherer et al observed that in ethnic groups expressing strong, numerous and branched A or B antigen sites, high bilirubin levels, severe anaemia, nucleated red cells and even hydrops fetalis was witnessed.
Group 5: Special causes (blood group incompatibilities, hydrops fetalis, congenital metabolic disease, twin-to-twin transfusion, tumor etc.
Fetal anaemia is one of the treatable causes of non-immune hydrops fetalis.
5 Pregnancies complicated by syphilis may result in intra-uterine growth restriction non-immune hydrops fetalis stillbirth preterm delivery and spontaneous abortion4.
The clinical manifestations of thalassemia can range from mild anemia with microcytosis ([beta]-thalassemia trait) to fatal Hb Barts hydrops fetalis (4 alpha-gene deletions).