hydrops fetalis


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Related to hydrops fetalis: erythroblastosis fetalis

hydrops

 [hi´drops] (L.)
old term for edema. adj., adj hydrop´ic.
fetal hydrops (hydrops feta´lis) gross edema of the entire body of the newborn infant, in erythroblastosis fetalis.

fe·tal hy·drops

, hydrops fetalis
abnormal accumulation of serous fluid in the fetal tissues, as in erythroblastosis fetalis.

hydrops fetalis

massive edema in the fetus or newborn, usually in association with severe erythroblastosis fetalis. Severe anemia and effusions of the pericardial, pleural, and peritoneal spaces also occur. The condition usually leads to death, even with immediate exchange transfusions after delivery. Also called fetal hydrops.

hydrops fetalis

Kernicterus, Rh incompatibility, Rh-induced hemolytic disease of newborn Obstetrics An accumulation of fluid in neonates, resulting in a 'puffy', plethoric or hydropic appearance that may be due to various etiologies Clinical Ascites, edema, ↓ protein or chronic intrauterine anemia, hepatosplenomegaly, cardiomegaly, extramedullary hematopoiesis, jaundice, pallor COD Heart failure. See Hemolytic disease of the newborn.
Hydrops Fetalis, causes
Immune Mother produces IgG antibodies against infant antigen(s), often an RBC antigen, most commonly, anti-RhD, which then passes into the fetal circulation, causing hemolysis
Non-immune Hydrops may result from various etiologies including
•  Fetal origin, eg congenital heart disease (premature foramen ovale closure, large AV septal defect), hematologic (erythroblastosis fetalis, α-thalassemia due to hemoglobin Barts, chronic fetomaternal or twin-twin transfusion), infection (CMV, herpesvirus, rubella, sepsis, toxoplasma), pulmonary (cystic adenomatoid malformation, diaphragmatic hernia, with pulmonary hypoplasia, lymphangiectasia), renal (vein thrombosis, congenital nephrosis) and teratomas, skeletal malformations (achondroplasia, osteogenesis imperfecta, fetal neuroblastomatosis, storage disease, meconium peritonitis, idiopathic)
•  Placental Chorangioma, umbilical or chorionic vein thrombosis
 Maternal DM, toxemia  

fe·tal hy·drops

, hydrops fetalis (fē'tăl hī'drops, fē-tā'lis)
Abnormal accumulation of serous fluid in the fetal tissues, as in erythroblastosis fetalis.

hydrops fetalis

The most severe form of HAEMOLYTIC DISEASE OF THE NEWBORN. The fetus dies in the womb from the overwhelming toxic effect of the BILIRUBIN released during excessive breakdown of red blood cells. See also RHESUS FACTOR.

Hydrops fetalis

A condition in which a fetus or newborn baby accumulates fluids, causing swollen arms and legs and impaired breathing.
References in periodicals archive ?
A 26-year-old gravida 3, para 1, abortus 2 woman was referred to the hospital at the 20th week of gestation because of hydrops fetalis.
Non-immune hydrops fetalis is a clinical picture characterized by diffuse edema.
SEA] breakpoints for prenatal diagnosis of Hb Barts hydrops fetalis.
It has been observed that large lesions have a higher risk to develop mediastinal shift, vascular failure, polyhydramniosis, hydrops fetalis and lung hypoplasia due to the effect of compression.
Thus, couples may be at risk for subsequent pregnancies complicated by hydrops fetalis.
We describe a novel technique that enables the simultaneous diagnosis of HbBarts hydrops fetalis and exclusion of maternal contamination.
Conclusion: The presented case of hydrops fetalis was due Kell alloimmunization that was detected during the postnatal period, and thus we plan to discuss the perinatal approach to Kell immunization.
Lysosomal storage diseases in non-immune hydrops fetalis pregnancies.
of alpha globin MCV (fl) MCH (pg) Phenotype genes Normal 4 90 +/- 5 30 +/- 2 Alpha thalassemia minor (mild) 3 81 +/- 7 26 +/- 2 Alpha thalassemia minor (severe) 2 69 +/- 4 22 +/- 2 HbH disease 1 65 +/- 7 19 +/- 2 Alpha thalassemia major, 0 110 to 120 Markedly Hb Barts, hydrops fetalis reduced Table 2.
After watching Rh-sensitized fetuses die from hydrops fetalis, he had the fortitude and skill to transfuse packed red blood cells intraperitoneally through the mother.
In the current case, we describe a neonate with hydrops fetalis and acute (transient) leukemia diagnosed on the basis of peripheral blood, bone marrow, and cytogenetic studies.