hydrolases


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Related to hydrolases: Isomerases, Ligases, Lyases, Acid hydrolases

hy·dro·las·es

(hī'drō-lās-ĕz),
Enzymes (EC class 3) cleaving substrates with addition of H2O at the point of cleavage, for example, esterases, phosphatases, nucleases, peptidases.
Synonym(s): hydrolyzing enzymes

hy·dro·las·es

(hī'drō-lās-ĕz)
Enzymes (EC class 3) cleaving substrates with addition of H2O at the point of cleavage.

hydrolases

Enzymes that promote the splitting of large molecules by attaching -OH from water to one moiety and -H from water to the other.
References in periodicals archive ?
Abide has developed a world class platform to discover potent and selective serine hydrolase inhibitors, which are one of the largest and most diverse classes of enzymes found in nature, which include lipases, esterases, thioesterases, amidases, peptidases and proteasesi.
Chen soon found, though, that one of the main target enzymes for JZL184 in worms was fatty acid amide hydrolase 4 (FAAH-4).
Tannase enzyme is tannin acyl hydrolase (EC 3.1.1.20) which can only hydrolyze the galloyl residues of galloyl esters of tannins and can be used in different industrial applications 4.
The third and fourth types are pullulan hydrolase I (neopullulanase) and pullulan hydrolase II (isopullulanase) (Duffner et al., 2000; Niehaus et al., 1999; Matzke et al., 2000) hydrolyze [alpha]-1,6 glycosidic bonds in pullulan while fifth type is pullulan hydrolase III has the ability to degrade [alpha]-1,4 and [alpha]-1,6 glycosidic linkages in pullulan (Niehaus et al., 2000; Ahmed et al., 2014).
The 5 proteins with increased expression levels were identified as type II peroxiredoxin 1, ATP-specific succinyl-CoA synthetase beta subunit, rho GDP-dissociation inhibitor 1, heme-binding protein, and phosphatidylethanolamine-binding protein 1, and the 11 proteins with decreased expression levels were identified as profilin-2, tubulin beta-5 chain, alpha-internexin, ketimine reductase mu-crystallin, L-lactate dehydrogenase B chain isoform 1, ubiquitin carboxy-terminal hydrolase L1, isoform CRA_a, proteasome subunit alpha type-3, N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, ferritin heavy chain, translationally controlled tumor protein, and prohibitin (Table 1).
Our results demonstrate that UPEC colonization leads to increased accumulation of proinflammatory oxylipids derived from the cyclooxygenase and soluble epoxide hydrolase pathways.
Cellobiohyrolases are a group of glycoside hydrolases, which hydrolyzed oligosaccharides of assorted lengths generated by endoglucanases to cellobiose (Ragauskas et al., 2006).
Bu et al., "Novel glycoside hydrolases identified by screening a chinese holstein dairy cow rumen-derived metagenome library," Applied and Environmental Microbiology, vol.
The deconjugation process is performed by bile salt hydrolase (BSH) enzyme produced by several microorganisms including bifidobacteria and lactobacilli (11,12).
Later studies with computerized molecular design and genetic engineering (76-80) generated various enzymes capable of hydrolyzing cocaine from human BChE, and these were called cocaine hydrolases (hCocE).
Two "chitinases" (glycoside hydrolases [GHs]) present on NELoc-1 are predicted to be involved in mucin degradation, as is the large carbohydrate-binding metalloprotease, shown to be involved in mucinase activity in other clostridia.
Based on reaction, Hydrolases enzyme segment dominated the market with around 77.9% market share in 2014.