Modification of pharmacokinetic and abuse-related effects of cocaine by human-derived cocaine hydrolase
In laboratory tests, synthetic versions of the glycoside hydrolase
domains applied to P.
The report provides comprehensive information on the Fatty Acid Amide Hydrolase
(FAAH or Anandamide Amidohydrolase or EC 22.214.171.124), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
'An association with reduced predicted bacterial bile salt hydrolase
gene abundance may be associated with a diminished capacity to metabolize bile acids," she said.
during fruit development in sweet and bitter almonds.
The UCHL1 gene is known as PARK5, and its mutations are associated with Parkinson disease ; indeed the I93M mutation shows severely diminished hydrolase
activity and lower E3 activity, while the S18Y mutant has greater hydrolase
activity but lower E3 activity than WT [37, 44].
Cygler, Lipases and alpha/beta hydrolase
Prunus serotina amygdalin hydrolase
and prunasin hydrolase
(2006) evaluated the influence of compost from (i) urban organic waste; (ii) green compost; (iii) herd manure and; (iv) sewage sludge on hydrolase
activity in a corn-wheat-barley crop rotation.
This enzymatic designation specifies hydrolases
(EC 3), which act on peptide bonds (EC 3.4), function as cysteine endopeptidases (EC 3.4.22), and are derived from the stem of bromelain (EC 126.96.36.199).
Background: Soluble epoxide hydrolase
(sEH) has been demonstrated to be a key enzyme involved in the pathologic development of several cardiovascular diseases and inflammation, and inhibition of sEH is therefore very helpful or crucial for the treatment of ischemia-reperfusion injury, cardiac hypertrophy, hypertension and inflammation.
Tannase or tannin acyl hydrolase
(EC 188.8.131.52) is an inducible enzyme produced by different microorganisms, such as bacteria (OSAWA et al., 2000; MONDAL et al., 2001) and fungi (BANERJEE et al., 2001; SAXENA; SAXENA, 2003; MUKHERJEE; BANERJEE, 2006).