hydrastine


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hy·dras·tine

(hī-dras'tēn),
An alkaloid of hydrastis; an isoquinoline chemically related to narcotine. (+) hydrastine is a GABA14 antagonist and convulsant.

hydrastine

(hī-drăs′tēn′, -tĭn)
n.
A poisonous white alkaloid, C21H21NO6, obtained from the root of the goldenseal and formerly used locally to treat inflammation of mucous membranes.
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Hydrastis canadensis (Goldenseal) is an herbaceous understory perennial, native to the eastern forests of North America, and is valued for its fleshy rhizomes, which contain the important alkaloids hydrastine and berberine.
Comments: Golden Seal contains hydrastine and berberine.
A better documented use for goldenseal is to combat "traveler's diarrhea." Two of the plant's chemical constituents, berberine and hydrastine, have proved to be effective remedies for such intestinal infections.