trademark for preparations of ergoloid mesylates, ergot alkaloids used to combat mild to moderate dementia in the elderly.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ergoloid mesylate

Alternative pharmacology
Any of a family of agents used in mainstream medicine to treat migraines. Some alternative medical doctors believe the ergoloid mesylates may be used to reverse age-associated mental impairment related to free radical damage, deposition of lipofuscin and reduced flow of oxygen caused by vasospasm, and have recommended their use for certain “off-label” applications, such as improving memory, treating depression, decreased motor skills and other forms of age-associated mental impairment.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Neurology A therapeutic cocktail used to alleviate some Sx of Alzheimer's disease, consisting of ergoloid mesylate–a 'metabolic enhancer,' hydergine's efficacy has not been well established. See Alzheimer's disease, Tacrine.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Out of 43 studies where herbal medicines were used as monotherapies, 37 reported that the herbal interventions exerted significantly greater effects than the conventional medicines (piracetam, aniracetam, hydergine, etc.) or placebos.
No difference in MMSE scores was identified between the Chinese herbal medicines and hydergine in 17 of the studies.
He was also prescribed Hydergine (which helped reduce symptoms briefly) at one point.
The patient had been treated with different psychotropic medications including antidepressants, antipsychotics, benzodiazepines, propranolol, fentazine and hydergine. Some had little effect like hydergine, whilst others worsened symptoms, in particular antipsychotic medications.
One study compared HM with Piracetam + hydergine and one study compared HM with Piracetam + vitamin E + respiratory stimulant Duxil (almitrine).
Use of hydergine in the treatment of leprosy ulcers.
* Hydergine had no effects in Alzheimer's patients at 3 mg/day and did not meet benefit standards at 6 mg/day.
One of the first smart drugs available in this country was hydergine, an extract of rye grain--more specifically a mold that grows on rye grain.
We use Prozac, Piracetam, Hydergine, and Deprenyl to modify our psychology, enhance our concentration, and slow brain aging.
Thompson, et al (N Engl J Med 1990; 323:445-8) found that Hydergine, the only drug currently FDA-approved for Alzheimer's, had no significant benefit in dementia, and may actually worsen dementia in a sub-set of patients.
Some contain imported drugs unapproved for use in this country, while others contain prescription drugs, such as ergoloid mesylates (brand name Hydergine).
Ads may be correct when they say that these drugs enhance mental function four times better than the ineffective drug Hydergine. But four times zero is still zero.