hydergine

Hydergine

[hi´der-jēn]

trademark for preparations of ergoloid mesylates, ergot alkaloids used to combat mild to moderate dementia in the elderly.

ergoloid mesylate

Alternative pharmacology
Any of a family of agents used in mainstream medicine to treat migraines. Some alternative medical doctors believe the ergoloid mesylates may be used to reverse age-associated mental impairment related to free radical damage, deposition of lipofuscin and reduced flow of oxygen caused by vasospasm, and have recommended their use for certain “off-label” applications, such as improving memory, treating depression, decreased motor skills and other forms of age-associated mental impairment.

hydergine

Neurology A therapeutic cocktail used to alleviate some Sx of Alzheimer's disease, consisting of ergoloid mesylate–a 'metabolic enhancer,' hydergine's efficacy has not been well established. See Alzheimer's disease, Tacrine.

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References in periodicals archive ?

Out of 43 studies where herbal medicines were used as monotherapies, 37 reported that the herbal interventions exerted significantly greater effects than the conventional medicines (piracetam, aniracetam, hydergine, etc.) or placebos.

No difference in MMSE scores was identified between the Chinese herbal medicines and hydergine in 17 of the studies.

Herbal Medicine for the Treatment of Vascular Dementia: An Overview of Scientific Evidence

He was also prescribed Hydergine (which helped reduce symptoms briefly) at one point.

The patient had been treated with different psychotropic medications including antidepressants, antipsychotics, benzodiazepines, propranolol, fentazine and hydergine. Some had little effect like hydergine, whilst others worsened symptoms, in particular antipsychotic medications.

25 years of hallucinogen persisting perception disorder--a diagnostic challenge

One study compared HM with Piracetam + hydergine and one study compared HM with Piracetam + vitamin E + respiratory stimulant Duxil (almitrine).

Herbal medicine and vascular dementia

Use of hydergine in the treatment of leprosy ulcers.

The history of a leprosy sanatorium in India. a literature review

* Hydergine had no effects in Alzheimer's patients at 3 mg/day and did not meet benefit standards at 6 mg/day.

Dementia. (The Effective Physician)

One of the first smart drugs available in this country was hydergine, an extract of rye grain--more specifically a mold that grows on rye grain.

HEALTHY AT EVERY AGE

We use Prozac, Piracetam, Hydergine, and Deprenyl to modify our psychology, enhance our concentration, and slow brain aging.

On becoming posthuman

Thompson, et al (N Engl J Med 1990; 323:445-8) found that Hydergine, the only drug currently FDA-approved for Alzheimer's, had no significant benefit in dementia, and may actually worsen dementia in a sub-set of patients.

Of dementia, depression and drugs

Some contain imported drugs unapproved for use in this country, while others contain prescription drugs, such as ergoloid mesylates (brand name Hydergine).

Can you buy "smart?" (products that allegedly increase intelligence)

Ads may be correct when they say that these drugs enhance mental function four times better than the ineffective drug Hydergine. But four times zero is still zero.